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LILRB3

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Part of Bioactivity data

CDA-H5250-MALS-HPLC
Human LILRB3, Fc Tag (Cat. No. ) MALS images

The purity of Human LILRB3, Fc Tag (Cat. No. CDA-H5250) is more than 90% and the molecular weight of this protein is around 150-185 kDa verified by SEC-MALS.

  • Background
    Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

    CDA-H52H9-MALS-HPLC
    Human LILRB3, His Tag (Cat. No. ) MALS images

    The purity of Human LILRB3, His Tag (Cat. No. CDA-H52H9) is more than 90% and the molecular weight of this protein is around 63-83 kDa verified by SEC-MALS.

Synonym Name

LILRB3,CD85a,ILT5

Background

Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcR¦Ã.

Clinical and Translational Updates

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