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BLAME

BLAME Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
BLE-H82E4 Human Biotinylated Human BLAME / SLAMF8 Protein, His Tag, Avi Tag (Avitag™)
BLE-H82E4-structure
BLE-H52H8 Human Human BLAME / SLAMF8 Protein, His Tag
BLE-H52H8-structure

BLAME Molecule Synonym Name

BLAME,SLAMF8,CD353

BLAME Molecule Background

BLAME (B-lymphocyte activator macrophage expressed) is also known as SLAM family member 8(SLAMF8), CD353. BLAME is a cell surface receptor that is expressed upon activation of macrophages (M?s) by IFN-? or bacteria, is a negative regulator of ROS in response to Gram+ and Gram- bacteria. May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. SLAMF8 is a costimulatory molecule that affects the activation of macrophages in inflammation and in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.

BLAME References

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