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BLAME

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Cat. No. Species Product Description Structure Purity Feature
BLE-H82E4 Human Biotinylated Human BLAME / SLAMF8 Protein, His,Avitag™
BLE-H82E4-structure
BLE-H82E4-sds
BLE-H82E4-elisa_1

Part of Bioactivity data

BLE-H82E4-BLI
Biotinylated Human BLAME, His,AvitagBiotinylated Human BLAME, His,Avitag (Cat. No. BLE-H82E4) ELISA bioactivity

Immobilized Human BLAME, His Tag at 2 μg/mL (100 μL/well) can bind Biotinylated Human BLAME, His,Avitag (Cat. No. BLE-H82E4) with a linear range of 1-31 ng/mL (QC tested).

Synonym Name

BLAME,SLAMF8,CD353

Background

BLAME (B-lymphocyte activator macrophage expressed) is also known as SLAM family member 8(SLAMF8), CD353. BLAME is a cell surface receptor that is expressed upon activation of macrophages (M?s) by IFN-? or bacteria, is a negative regulator of ROS in response to Gram+ and Gram- bacteria. May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. SLAMF8 is a costimulatory molecule that affects the activation of macrophages in inflammation and in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.

Clinical and Translational Updates

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