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FGL1

FGL1 Part of Bioactivity data

FG1-H82Ey-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

FACS assay shows that Biotinylated Human FGL1, His,Avitag (Cat. No. FG1-H82Ey) can bind to 293T cells overexpressing Human LAG3. The concentration of Human FGL1 is 10 μg/mL (Routinely tested).

FG1-H82F4-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

FACS analysis shows that Biotinylated Human FGL1, Avitag,Fc Tag (Cat. No. FG1-H82F4) can bind to 293T cells overexpressing human LAG3. The concentration of Human FGL1 is 10 μg/mL (Routinely tested).

FG1-H82F6-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Biotinylated Human FGL1 (64-312), Avitag,Fc Tag (Cat. No. FG1-H82F6) on SA Biosensor, can bind Human LAG-3, Fc Tag (HPLC-verified) (Cat. No. LA3-H5255) with an affinity constant of 3.78 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

FG1-H82F4-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Biotinylated Human FGL1, Avitag,Fc Tag (Cat. No. FG1-H82F4) on SA Biosensor, can bind Human LAG-3, Fc Tag (Cat. No. LA3-H5255) with an affinity constant of 4.12 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

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FGL1 Molecule Synonym Name

FGL1,Hepassocin,HP-041,HFREP-1,LFIRE-1,HFREP1

FGL1 Molecule Background

Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.

FGL1 References

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