Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > IL-1RL1


Brief Information

Name:Interleukin-1 receptor-like 1
Target Synonym:ST2,IL1RL1,Protein ST2,DER4,T1,Interleukin 1 Receptor Like 1,Homolog Of Mouse Growth Stimulation-Expressed,Interleukin 1 Receptor-Related Protein,Growth Stimulation-Expressed,FIT-1,IL33R,ST2L,ST2V,Interleukin-1 Receptor-Like 1 Protein,EC:,Interleukin-1 Receptor-Like 1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:5
Lastest Research Phase:NDA/BLA

Product ListCompare or Buy

ACRO Quality

Part of Bioactivity data


Loaded Human IL-1RL1, Fc Tag (Cat. No. IL1-H5250) on Protein A Biosensor, can bind with Biotinylated Human IL-33, His,Avitag (Cat. No. IL3-H82H5) an affinity constant of 1.81 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).


Immobilized Human IL-33 Protein, His Tag, premium grade(Cat. No. IL3-H52H7) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-1RL1, His,Avitag (Cat. No. IL1-H82E9) with a linear range of 0.3-10 ng/mL (QC tested).

Synonym Name



Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.

Clinical and Translational Updates

Related Molecule

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Astegolimab AMG-282; RG-6149; RO-7187807 Phase 3 Clinical Amgen Inc, F. Hoffmann-La Roche Ltd Coronavirus Disease 2019 (COVID-19); Pulmonary Disease, Chronic Obstructive; Dermatitis, Atopic Details
Recombinant humanized anti-ST2 monoclonal antibody 9-MW1911; 9MW-1911; 9-MW-1911; 9MW1911 Phase 2 Clinical Mabwell (Shanghai) Bioscience Co Ltd Asthma; Pulmonary Disease, Chronic Obstructive; Dermatitis, Atopic Details
Melrilimab GSK-3772847; CNTO-7160 Phase 2 Clinical Johnson & Johnson Innovative Medicine Asthma Details
TQC-2938 TQC2938; TQC-2938 Phase 1 Clinical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group Asthma Details

This web search service is supported by Google Inc.

Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
+1 888-377-6111
1 Innovation Way, Newark, DE 19711, USA

Leave a message