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E2

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Cat. No. Species Product Description Structure Purity Feature
E2P-C52H7 Hepacivirus C Hepacivirus C E2 Protein, His Tag
E2P-C52H7-structure

E2 Molecule Synonym Name

E2

E2 Molecule Background

Glycoprotein E2 is an approximately 50 kDa viral envelope protein encoded by the hepatitis C virus (HCV) genome. HCV infection often progresses to severe, liver-associated diseases, such as cirrhosis, steatosis, and hepatocellular carcinoma. Both E1 and E2 are essential for infectivity, with E2 possessing the binding sites for the entry receptors CD81 and SCARB1.Moreover, glycoprotein E2 is BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells.

E2 References

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