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Your Position: Home > All Other Proteins > EMMPRIN > CD7-HF222

FITC-Labeled Human EMMPRIN / CD147 Protein, His Tag

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  • Synonym
    Basigin,BSG,5F7,CD147,EMMPRIN,M6,OK,TCSF
  • Source
    FITC-Labeled Human EMMPRIN, His Tag (CD7-HF222) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - His 205 (Accession # P35613-2). It is the FITC labeled form of Human EMMPRIN, His Tag (CD7-H5222).
    Predicted N-terminus: Ala 22
  • Molecular Characterization
    Online-Res(Ala 22 - His 205) P35613-2

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 20.9 kDa.

  • Conjugate

    FITC

    Excitation source: 488 nm spectral line, argon-ion laser

    Excitation Wavelength: 488 nm

    Emission Wavelength: 535 nm

  • Labeling
    The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with FITC using standard chemical labeling method. The residual FITC is removed by molecular seive treatment during purification process.
  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 12 months under sterile conditions after reconstitution.
  • Background
    CD147 is also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.
  • References
    • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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    Order Details

    Price(USD) : $319.00

    Price(USD) : $1980.00

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    Drug Development Status

    • Number of Launched Drugs:1 Details
    • Number of Drugs in Clinical Trials:3 Details
    • Latest Research Phase:Approved

    Datasheet & Documentation

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    DMF (Drug Master File)

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