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Your Position: Home > All Other Proteins > Mucin-1 > MU1-H5153

Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag

  • Synonym
    Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1,SEC,MUC-1,X,MUC1,ZD,PEM,PEMT,PUM,CA15-3,Episialin
  • Source
    Human Mucin-1 (116-173), Fc Tag (MU1-H5153) is expressed from E.coli cells. It contains AA Ser 116 - Gly 173 (Accession # P15941-8).
    Predicted N-terminus: Ser 116
  • Molecular Characterization
    Online(Ser 116 - Gly 173) P15941-8

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 32.7 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human Mucin-1 (116-173), Fc Tag (Cat. No. MU1-H5153) SDS-PAGE gel

Human Mucin-1 (116-173), Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:16 Details
  • Latest Research Phase:Phase 3 Clinical

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