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Your Position: Home > TME Relevant Pathway > CXCL4 > CX4-H52H9

Human CXCL4 / PF4 Protein, His Tag

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    PF4,CXCL4,MGC138298,SCYB4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A
  • Source
    Human CXCL4, His Tag (CX4-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 32 - Ser 101 (Accession # P02776-1).
    Predicted N-terminus: Glu 32
  • Molecular Characterization
    Online-Res(Glu 32 - Ser 101) P02776-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 9.6 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    CXCL4, or Platelet factor 4 (PF4), is a small cytokine belonging to the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. CXCL4 is chemotactic for neutrophils and monocytes and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. CXCL4/PF4 is up-regulated in human liver fibrosis and that it plays a nonredundant, functional role in experimental liver fibrosis by mediating stellate cell proliferation, migration, and intrahepatic immune cell recruitment.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $400.00

Price(USD) : $2640.00

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