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Browse By Molecule Name --->CCL6 / SCYA6 Molecule

CCL6 / SCYA6 Molecule  


CCL6 / C10 Molecule Synonym Name

CCL6,SCYA6,C10,MRP-1

CCL6 / C10 Protein Products

Cat No Species Product Description
CC6-M5222 Mouse Mouse CCL6 / C10 Protein

CCL6 / C10 Molecule Background

Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GM­CSF. CCL6 has only been identified in rodents, A human homologue for mouse CCL6 has not been identified. The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid residue mature protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, where it is strongly induced upon GM­CSF (Cat. # GMF-H4214) stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 (Cat. # IL4-H4218) in mouse macrophages and by cytokine IL­13 (Cat. # IL3-H4210) in mouse lung. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.

Reference

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