GPA33 / A33 Molecule
GPA33 / A33 Molecule Synonym Name
GPA33 / A33 Protein Products
|Cat No||Species||Product Description|
|GP3-H5224||Human||Human GPA33 / A33 Protein|
|GP3-H8224||Human||Biotinylated Human GPA33, ultra sensitivity (primary amine labeling)|
|GP3-M5225||Mouse||Mouse GPA33 / A33 Protein|
GPA33 / A33 Molecule Background
Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.
- (1) Heath JK., et al., 1997, Proc Natl Acad Sci U S A 94 (2): 469–74.
- (2) Ritter G., et al., 1997, Biochem Biophys Res Commun 236 (3): 682–6.