CD160 / BY55 Molecule
CD160 / BY55 Molecule Synonym Name
CD160, BY55, NK1, NK28
CD160 / BY55 Protein Products
|Cat No||Species||Product Description|
|BY5-H5229||Human||Human CD160 /BY55 Protein|
CD160 / BY55 Molecule Background
CD160 antigen also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.
- (1) Anumanthan A., et al., 1998, J. Immunol. 161:2780-2790.
- (2) Agrawal S., et al., 1999, J. Immunol. 162:1223-1226.