ADAM8 / MS2 Molecule
ADAM8 / CD156a Molecule Synonym Name
ADAM8 / CD156a Protein Products
|Cat No||Species||Product Description|
|AD8-H5223||Human||Human ADAM8 / CD156a Protein|
ADAM8 / CD156a Molecule Background
Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.
- (1) Yoshiyama K., et al., 1997, Genomics 41 (1): 56–62.
- (2) Hall T., et al., 2012, Acta Crystallogr. F 68:616-621.