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Browse By Molecule Name --->CD47 Molecule

CD47 Molecule  


CD47 Molecule Synonym Name

CD47,MER6,IAP,OA3

CD47 Protein Products

Cat No Species Product Description
CD7-C5252CynomolgusCynomolgus CD47 Protein, Fc Tag
CD7-H5227HumanHuman CD47 Protein
CD7-H5256HumanHuman CD47 Protein, Fc Tag (HPLC-verified)
CD7-H52A5HumanHuman CD47 Protein, mouse IgG2a Fc Tag, low endotoxin
CD7-H82F6HumanBiotinylated Human CD47, Fc Tag, Avi Tag (Avitag?)
CD7-M5251MouseMouse CD47 Protein, Fc Tag
CD7-R5256RatRat CD47 Protein, Fc Tag
CD7-R5257RabbitRabbit CD47 Protein, Fc Tag
CD7-H82E9HumanBiotinylated Human CD47 Protein, Avi Tag (Avitag?)
CD7-HA2E9HumanUnconjugated Human CD47 Protein, His Tag & Avi Tag

CD47 Molecule Background

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

Reference

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