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Browse By Molecule Name --->PDL2 / B7-DC Molecule

PDL2 / B7-DC Molecule  


PD-L2 / B7-DC Molecule Synonym Name

PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2

PD-L2 / B7-DC Protein Products

Cat No Species Product Description
PD2-H5220 Human Human PD-L2 / B7-DC Protein
PD2-H5251 Human Human PD-L2 / B7-DC Protein, Fc Tag (HPLC-verified)
PD2-H52A5 Human Human PD-L2 / B7-DC Protein, mouse IgG1 Fc Tag
PD2-H82E8 Human Biotinylated Human PD-L2 / B7-DC Protein (recommended for biopanning), Avi Tag (Avitag?)
PD2-M5254 Mouse Mouse PD-L2 / B7-DC Protein, Fc Tag
PD2-M52A5 Mouse Mouse PD-L2 / B7-DC Protein, mouse IgG2a Fc Tag, low endotoxin
PD2-M52E3 Mouse Mouse PD-L2 / B7-DC Protein
PD2-H82F6 Human Biotinylated Human PD-L2 / B7-DC, Fc Tag, Avi Tag (Avitag™)

PD-L2 / B7-DC Molecule Background

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Reference

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