TXN2 / TRX2 Molecule
Thioredoxin-2 Molecule Synonym Name
Thioredoxin-2 Protein Products
|Cat No||Species||Product Description|
|TX2-H5141||Human||Human Thioredoxin-2 / TXN2 Protein|
Thioredoxin-2 Molecule Background
Thioredoxin-2 (TXN2),a member of the thioredoxin family,is also known as mitochondrial (MTRX or Mt-Trx) and TRX2.TXN2 have two important domains: Redox-active center and Transit peptide. TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Also, TXN2 could be involved in the resistance to anti-tumor agents. TNX2 possesses a dithiol-reducing activity as well.
- (1) Chen Y., et al., 2002, J. Biol. Chem. 277:33242-33248.
- (2) Damdimopoulos A.E., et al., 2002, J. Biol. Chem. 277:33249-33257.
- (3) Smeets A., et al., 2005, Protein Sci. 14:2610-2621.