CA14 / CA-XIV Molecule
CA14 Molecule Synonym Name
CA14 Protein Products
|Cat No||Species||Product Description|
|CA4-H5227||Human||Human Carbonic Anhydrase XIV / CA14 Protein|
CA14 Molecule Background
Carbonic anhydrase XIV (CA14),a member of the alpha-carbonic anhydrase family, is also known as carbonate dehydratase XIV, which is a single-pass type I membrane protein. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA14 shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. As for tissue specificity,CA14 is high expressed in all parts of the central nervous system and lower expressed in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle.
- (1) Temperini C., et al., 2006, Chemistry 12:7057-7066.
- (2) Di Fiore A., et al., 2009, Proteins 74:164-175.
- (3) Alterio V., et al., 2014, Biopolymers 101:769-778.