Recombinant Human S100A14 Protein (rh S100A14) Met 1 - His 104 (Accession # AAH05019) was produced in E.coli cells at ACROBiosystems.
rh S100A14 is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 12.5 kDa. The predicted N-terminus is Met 1. DTT-reduced Protein migrates as 13 kDa in SDS-PAGE .
Less than 1.0 EU per μg of the rh S100A14 by the LAL method.
>92% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in 50 mM Tris,150 mM NaCl,pH8.0. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Contact us for customized product form or formulation.
See Certificate of Analysis for reconstitution instructions and specific concentrations.
Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).
Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.