Browse Products By Molecule:

This web search service is supported by Google Inc.

Products --> Other Recombinant Proteins

Human S100A10 Protein  pdf  pdf  pdf


Cat-Pack Size Price(USD) Qty Inventory Order
Quote for bulk   Worldwide Shipping & Payment
S10-H5127-100ug
    $250.00
S10-H5127-1mg
    $1300.00
In-stock
Place Purchase Orders


Synonym

S100A10,p11,p10,ANX2LG,CAL1L,CLP11

Source

Recombinant Human S100A10 Protein (rh S100A10) Met 1 - Lys 97 (Accession # AAH15973) was produced in E.coli cells at ACROBiosystems.

Molecular Characterization

rh S100A10 is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 12 kDa. The predicted N-terminus is Met. DTT-reduced Protein migrates as 12 kDa in SDS-PAGE .

Endotoxin

Less than 1.0 EU per μg of the rh S100A10 by the LAL method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM Tris,150 mM NaCl,pH8.0. Normally Mannitol or Trehalose are added as protectants before lyophilization.

Contact us for customized product form or formulation.

Reconstitution

See Certificate of Analysis for reconstitution instructions and specific concentrations.

Storage

Avoid repeated freeze-thaw cycles.

No activity loss was observed after storage at:
In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).

 

SDS-PAGE


Recombinant Human S100A10  Protein
The purity of rh S100A10 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
 
 

Background

S100 calcium-binding protein A10 (S100A10), a member of the S100 family of proteins containing two EF-hand calcium-binding motifs, is also known as protein S100-A10, calpactin I light chain, cellular ligand of annexin II, p10 protein and p11, which can be found as a free monomer, a homodimer, or a heterotetramer composed of a p11 dimer complex with two molecules of annexin II. S100A10 is an integral part of cellular structural scaffolding that interacts with plasma membrane proteins through its association with annexin II. S100A10 also works together with cytosolic and peripheral membrane-associated proteins such as AHNAK in the development of the intracellular membrane. Furthermore,S100A10 has been implicated in the transportation of proteins involved in mood regulation, nociception, and cell polarization. Complexed with the annexin II, S100A10 binds receptor and channel proteins and guides them to the cell surface, resulting in increased membrane localization and consequent magnified functional expression of these proteins.

Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.


References