Browse Products By Molecule:

Products --> Other Recombinant Proteins

Human BTN1A1 / Butyrophilin Protein, Fc Tag  pdf  pdf  pdf


Cat-Pack Size Price(USD) Qty Inventory Order
Quote for bulk   Worldwide Shipping & Payment
BT1-H5253-100ug
    $290.00
BT1-H5253-1mg (500ug x 2)
    $1980.00
In-Stock
Place Purchase Orders


Synonym

BTN1A1, Butyrophilin, BTN

Source

Human BTN1A1 / Butyrophilin Protein, Fc Tag, Ala 27 - Arg 242 (Accession # AAH96312) was produced in human 293 cells (HEK293) at ACROBiosystems.

Molecular Characterization

BTN1A1 (Ala 27-Arg 242)AAH96312

Fc (Pro 100-Lys 330)P01857

Human BTN1A1, Fc Tag is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 50.6 kDa. The predicted N-terminus is Ala 27. As a result of glycosylation, the reducing (R) protein migrates as 55-66 kDa, and the non-reducing (NR) protein migrates as 116-130 kDa in SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

Reconstitution

See Certificate of Analysis for reconstitution instructions and specific concentrations.

Storage

Avoid repeated freeze-thaw cycles.

No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).

 

SDS-PAGE


Human BTN1A1 / Butyrophilin Protein, Fc Tag
Human BTN1A1, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
 
 

Background

Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.


References