Browse Products By Molecule:

This web search service is supported by Google Inc.

Products --> Other Recombinant Proteins

Human VSIG4 Protein  pdf  pdf  pdf


Cat-Pack Size Price(USD) Qty Inventory Order
Quote for bulk   Worldwide Shipping & Payment
VS4-H5226-100ug
    $250.00
VS4-H5226-1mg
    $1440.00
In-stock
Place Purchase Orders


Synonym

VSIG4,CRIg,Z39IG

Source

Human VSIG4, His Tag (VS4-H5226) is expressed from human 293 cells (HEK293). It contains AA Arg 20 - Pro 283 (Accession # AAH10525).

Predicted N-terminus: Arg 20

Molecular Characterization

VSIG4(Arg 20 - Pro 283)AAH10525
Poly-his

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 30 kDa. The protein migrates as 45-48 kDa under reducing (R) condition (SDS-PAGE).

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

No activity loss is observed after storage at:

  1. 4-8°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

SDS-PAGE

Human VSIG4, His Tag (Cat. No. VS4-H5226) SDS-PAGE gel

Human VSIG4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

 

Background

V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.

References

Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.


Related Products