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IL-6 / IFNB2 / BSF2 Molecule  


IL-6 Molecule Synonym Name

IL6,HGF,Interleukin-6,BSF2,HSF,IFNB2

IL-6 Protein Products

Cat No Species Product Description
IL6-H4218 Human ActiveMax® Recombinant Human IL-6
IL6-H8218 Human Biotinylated Human IL-6, epitope tag free, ultra sensitivity (primary amine labeling)

IL-6 Molecule Background

Interleukin 6 (IL-6) is also known as HGF, BSF2,HSF, IFNB2 and IL-6, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts,endothelial cells,et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes,atherosclerosis, depression,Alzheimer's Disease,systemic,lupus erythematosus,prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood.Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.

Reference

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