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Browse By Molecule Name --->IL-17A / CTLA-8 Molecule

IL-17A / CTLA-8 Molecule  


IL-17A / CTLA-8 Molecule Synonym Name

IL-17A,Interleukin-17A,CTLA-8,IL-17

IL-17A / CTLA-8 Protein Products

Cat No Species Product Description
ILA-H5118 Human Human IL17 / IL17A Protein, Tag Free 
CT8-M5240 Mouse Mouse IL-17A / CTLA-8 Protein

IL-17A / CTLA-8 Molecule Background

Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Reference

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