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Your Position: Home > Protein > CCL4 > CC4-H51H3

Human CCL4 Protein, His Tag

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This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    C-C motif chemokine 4,G-26 T-lymphocyte-secreted protein,HC21,Lymphocyte activation gene 1 protein,LAG-1,MIP-1-beta(1-69),Macrophage inflammatory protein 1-beta,MIP-1-beta,PAT 744,Protein H400,SIS-gamma,Small-inducible cytokine A4,T-cell activation protein 2,ACT-2,CCL4,LAG1,MIP1B,SCYA4
  • Source
    Human CCL4 Protein, His Tag(CC4-H51H3) is expressed from E. coli cells. It contains AA Ala 24 - Asn 92 (Accession # P13236-1).
    Predicted N-terminus: Met
  • Molecular Characterization
    CCL4 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 9.7 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    CCL4, also know as MIP-1-beta, is monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
  • Clinical and Translational Updates

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Price(USD) : $350.00

Price(USD) : $2310.00

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Drug Development Status

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  • Number of Drugs in Clinical Trials:0 Details
  • Latest Research Phase:Preclinical

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