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> Redeem your test We appreciate your continued support! To express our gratitude, we’re offering a stylish T-shirt with new purchase of our Multi-Pass Transmembrane Proteins (TPs). These challenging proteins are critical drug targets in cancer and other diseases, but their complexity hinders research. We address this by offering three robust platforms to meet your specific needs:
Explore Our Diverse TP Portfolio
Case Studies: Highlighting the Quality and Functionality
Full-length Claudin18.2-VLP (Cat. No. CL2-H52P7) has been observed under an electron microscope to ensure that it is assembled correctly.
Immobilized Human Claudin-18.2 Full Length Protein-VLP (Cat. No. CL2-H52P7) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Chimeric Claudin-18.2 Antibody, Human IgG1 with a linear range of 0.2-3 ng/mL (QC tested).
Human Claudin-18.2 Full Length Protein-VLP (Cat. No. CL2-H52P7) captured on CM5 Chip via Anti-Claudin-18.2 antibody can bind Anti-Claudin-18.2 antibody with an affinity constant of 0.374 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
The mean peak Radius of VLP is 65-85 nm with more than 95% intensity as determined by dynamic light scattering (DLS).
Immobilized Rituximab at 2 μg/mL (100 μL/well) can bind Biotinylated Human CD20 Full Length, His,Avitag (Cat. No. CD0-H82E5) with a linear range of 4-63 ng/mL (in presence of DDM and CHS) (QC tested).
Biotinylated Human CD20 Full Length, His,Avitag (Cat. No. CD0-H82E5) captured on Biotin CAP-Series S Sensor Chip can bind Rituximab with an affinity constant of 1.73 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore T200) (QC tested).
Fluorescent Human Claudin-6 Protein, Flag, His, GFP Tag (Cat. No. CL6-HF2M9) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 80%.
Immobilized Fluorescent Human Claudin-6 Protein, Flag, His, GFP Tag (Cat. No. CL6-HF2M9) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human Claudin 6 antibody, Human IgG1 with a linear range of 0.1-3 ng/mL (QC tested).
2e5 of anti-Claudin-6 CAR-293 cells were stained with 100 μL of 1 μg/mL of Fluorescent Human Claudin-6 Protein, Flag, His, GFP Tag (Cat. No. CL6-HF2M9) and negative control protein respectively (Fig. A and B), FITC signal was used to evaluate the binding activity (QC tested).
Four-pass TPs: CD20, Claudin 18.2, Claudin 6
Five-pass TP: CD133
Seven-pass TPs/GPCRs:GPRC5D, CXCR4, CCR5, CCR8
Eight-pass TP: SLC1A2
Twelve-pass TP: SLC7A11 & SLC3A2
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How to participate:1. Fill out the form below & receive the discount code via email.
2. Redeem your code during checkout on the ACRO's website.
3. If ordering through your account manager, please provide the code with your products inquires or reference it in your purchase order.
Order Now and Advance Your Research!
1. Campaign Date: Apr. 26th, 2024 – Jun. 30th, 2024
2. Promo codes cannot be combined with other discounts or codes in the same order. Promo codes can only be used once.
3. Orders must be placed directly with ACROBiosystems. Offer is not valid on orders placed through our extended distributor network.
4. Campaign participating countries: Europe.
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6. ACROBiosystems reserves all rights for final explanation
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