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| Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
| CLDN6 mAb - 01 | PCC | Solid Tumor | Ovarian cancer,Lung adenocarcinoma |
Expression analysis of human Claudin-6 on HEK293/Human Claudin-6 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Claudin-6 Stable Cell Line or negative control cell using anti-human Claudin-6 antibody followed by PE anti-human IgG Fc antibody after fixation with 4% paraformaldehyde.
Anti-Claudin 6 antibody, Human IgG1 captured on Protein A Chip can bind Biotinylated Human Claudin-6 Full Length Protein, His,Avitag&FlagTag (Cat. No. CL6-H85D4) with an affinity constant of 36.5 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| IMAB-027 | ASP-1650; IMAB-027 | Phase 2 Clinical | Ganymed | Ovarian Neoplasms; Neoplasms; Neoplasms, Germ Cell and Embryonal | Details |
| TORL-1-23 | TORL-1-23 | Phase 2 Clinical | Torl Biotherapeutics LLC | Solid tumours; Ovarian Neoplasms; Carcinoma, Ovarian Epithelial; Endometrial Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Peritoneal Diseases | Details |
| BNT-142 | BNT-142 | Phase 2 Clinical | Biontech Se | Solid tumours | Details |
| BGB-B455 | BGB-B455 | Phase 1 Clinical | BeOne Medicines Ltd | Solid tumours | Details |
| AT03-65 | AT03-65; AT-03-65 | Phase 1 Clinical | Axcynsis Therapeutics Pte Ltd | Solid tumours | Details |
| CTIM-76 | CTIM-76 | Phase 1 Clinical | Integral Molecular Inc | Ovarian Neoplasms; Solid tumours; Neoplasms; Testicular Neoplasms; Endometrial Neoplasms | Details |
| NBL-028 | NBL028; NBL-028 | Phase 1 Clinical | Shanghai Xinshi Biological Medicine Co Ltd, Novarock Biotherapeutics Ltd | Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Neoplasms; Testicular Neoplasms; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| XmAb-541 | XmAb541; XmAb-541 | Phase 1 Clinical | Xencor Inc | Ovarian Neoplasms; Ovarian germ cell tumor; Endometrial Neoplasms; Germinoma; Neoplasms, Germ Cell and Embryonal | Details |
| SAIL-66 | SAIL-66; SAIL66 | Phase 1 Clinical | Chugai Pharmaceutical Co Ltd | Solid tumours | Details |
| CLDN6-CAR-NK Cell Therapy | Phase 1 Clinical | Second Affiliated Hospital Of Guangzhou Medical University | Ovarian Neoplasms; Testicular Neoplasms; Endometrial Neoplasms | Details | |
| DS-9606a | DS-9606a; DS-9606-a | Phase 1 Clinical | Daiichi Sankyo Inc | Ovarian Neoplasms; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neoplasm Metastasis | Details |
| CLDN6 CAR-T cell therapy (BioNTech) | BNT-211 | Phase 1 Clinical | Biontech Se | Solid tumours | Details |
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