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CCR5

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Cat. No. Species Product Description Structure Purity Feature
CC5-H52D1 Human Human CCR5 Protein, Flag,His Tag
CC5-H52D1-structure
CC5-H52D1-sds
CC5-H52D1-elisa_1
CC5-H52D1-elisa_2

CCR5 Part of Bioactivity data

CC5-H52D1-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human CCR5, Flag,His Tag (Cat. No. CC5-H52D1) captured on CM5 chip via anti-His antibody can bind Anti-CCR5 antibody (Human IgG1) with an affinity constant of 0.0737 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore T200) (Routinely tested).

CC5-H52D1-SPR
Human_FcRn_Heterodimer_Protein_SPR

Purified NA/LE Mouse Anti-Human CD195 (Clone: 2D7) (Mouse IgG2a) captured on CM5 chip via anti-mouse antibodies surface can bind Human CCR5, Flag,His Tag (Cat. No. CC5-H52D1) with an affinity constant of 7.51 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore T200) (Routinely tested).

CCR5 Molecule Synonym Name

CCR5,CMKBR5,CD195,CC-CKR-5,CHEMR13

CCR5 Molecule Background

Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.

CCR5 References

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