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Your Position: Home > CD99

CD99

Brief Information

Name:CD99 antigen
Target Synonym:12E7,E2 antigen,Protein MIC2,T-cell surface glycoprotein E2
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
CD9-H5254 Human Human CD99 / MIC2 Protein, Llama IgG2b Fc Tag, low Endotoxin (MALS verified)
CD9-H5254-structure
CD9-H5254-sds
HGS-S263 Rabbit Recombinant Monoclonal Anti-CD99 Antibody, Rabbit (4F5)
CD9-H82E7 Human Biotinylated Human CD99 / MIC2 Protein, His,Avitag™
CD9-H82E7-structure
CD9-H82E7-sds
CD9-HF254 Human FITC-Labeled Human CD99 / MIC2 Protein, Fc Tag
CD9-HF254-structure
CD9-HF254-sds
CD9-H5221 Human Human CD99 / MIC2 Protein, His Tag
CD9-H5221-structure
CD9-H5221-sds
ACRO Quality

Part of Bioactivity data

CD9-H5254-ELISA
CD99 MALS images

The purity of Human CD99 Protein, Llama IgG2b Fc Tag (Cat. No. CD9-H5254) is more than 85% and the molecular weight of this protein is around 75-90 kDa verified by SEC-MALS.

Synonym Name

CD99,HBA71,MIC2,MIC2X,MIC2Y,MSK5X,12E7

Background

CD99 antigen is also known as MIC2, single-chain type-1 glycoprotein, HBA71, MIC2X, MIC2Y, MSK5X, 12E7, which belongs to the CD99 family. CD99 / MIC2 is expressed on all leukocytes but highest on thymocytes. Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 / MIC2 plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. CD99 acts at the same site as, but independently of PECAM1. There is also experimental evidence that it binds to cyclophilin A.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Anti-CD99 CAR T-cell therapy (Wuhan Bio-Raid) BRD-03 Phase 2 Clinical Wuhan BioRaid Biotechnology Co Ltd Sarcoma; Osteosarcoma Details

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