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Your Position: Home > Protein > DDC > DDC-H55H6

Human DDC / Dopa Decarboxilase Protein, His Tag

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  • Synonym
    Aromatic-L-amino-acid decarboxylase,Dopa decarboxilase,AADC
  • Source
    Human DDC, His Tag (DDC-H55H6) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Glu 480 (Accession # P20711-1).
    Predicted N-terminus: Met 1
  • Molecular Characterization
    Online-Res(Met 1 - Glu 480) P20711-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 55.8 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Shipping
    This product is supplied and shipped with dry ice, please inquire the shipping cost.
  • Background
    Dopa decarboxilase (DDC), also known as aromatic amino acid decarboxylase, is a group II decarboxylase. The enzyme catalyzes the decarboxylation of aromatic L-amino acids to produce the corresponding amines. DDC produces the neurotransmitters dopamine and serotonin from L-Dopa and L-5-hydroxytryptophan, respectively. DDC inhibitors is in clinical use to treat Parkinson's disease(PD), usually co-administrated with L-DOPA. DDC would block peripheral conversion to dopamine and allow a greater percentage of L-DOPA to reach the brain, causing an increase in brain dopamine levels, and reducing the side effects of dopamine-rich blood.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $240.00

Price(USD) : $2160.00

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Drug Development Status

  • Number of Launched Drugs:8 Details
  • Number of Drugs in Clinical Trials:9 Details
  • Latest Research Phase:Approved

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