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Your Position: Home > Protein > beta-Galactosidase-1 > BG1-H52H3

Human beta-Galactosidase-1 Protein, His Tag (active enzyme)

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  • Synonym
    EBP, ELNR1, MPS4B
  • Source
    Human beta-Galactosidase-1 Protein, His Tag(BG1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 24 - Val 677 (Accession # P16278-1).
    Predicted N-terminus: Leu 24
  • Molecular Characterization
    beta-Galactosidase-1 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 75.5 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, 20% Glycerol, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
SDS-PAGE
beta-Galactosidase-1 SDS-PAGE

Human beta-Galactosidase-1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity

Measured by its ability to cleave a fluorogenic substrate, 4-Methylumbelliferyl-β-D-galactopyranoside. The specific activity is >1,800 pmol/min/μg, as measured under the described conditions(QC tested).

  • Background
    This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome. [provided by RefSeq, Nov 2015]
  • Clinical and Translational Updates

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Price(USD) : $350.00

Price(USD) : $2500.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 2 Clinical

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