0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > GUCY2C

GUCY2C

GUCY2C Protein Product ListCompare or Buy

GUCY2C Part of Bioactivity data

GUC-HF2H8-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

2e5 of Anti-GUCY2C CAR-293 cells were stained with 100 μL of 1 μg/mL of FITC-Labeled Human GUCY2C, His Tag (Cat. No. GUC-HF2H8) and negative control protein respectively, FITC signal was used to evaluate the binding activity(QC tested).

GUC-H52H5-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

2e5 of anti-GUCY2C CAR-293 cells were stained with 100 µL of 1 µg/mL Human GUCY2C, His Tag (Cat. No. GUC-H52H5) and negative control protein respectively, washed and then followed by PE anti-His antibody and analyzed with FACS (Routinely tested).

GUC-C5255-ELISA
Cynomolgus GUCY2C, Fc TagCynomolgus GUCY2C, Fc Tag (Cat. No. GUC-C5255) ELISA bioactivity

Immobilized Cynomolgus GUCY2C, Fc Tag (Cat. No. GUC-C5255) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human GUCY2C Antibody, Human IgG1 (Cat. No. GUC-M78) with a linear range of 0.1-3 ng/mL (QC tested).

GUC-H82E9-ELISA
Biotinylated Human GUCY2C, His,AvitagBiotinylated Human GUCY2C, His,Avitag (Cat. No. GUC-H82E9) ELISA bioactivity

Immobilized Biotinylated Human GUCY2C, His,Avitag (Cat. No. GUC-H82E9) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate, can bind Monoclonal Anti-Human GUCY2C Antibody, Human IgG1 with a linear range of 0.2-2 ng/mL (QC tested).

GUCY2C Molecule Synonym Name

GUCY2C,GUC2C,STAR,STA receptor,hSTAR,GC-C

GUCY2C Molecule Background

GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.

GUCY2C References

This web search service is supported by Google Inc.

totop