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| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| JA1-H5547 | Human | Human JAK1 Protein, His Tag |  |
|
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Filgotinib Maleate | G-146034-101; GS-6034; G-146034; GLPG-0634 | Approved | Galapagos Nv | Jyseleca | EU | Arthritis, Rheumatoid | Galapagos Nv | 2020-09-24 | Lupus Erythematosus, Cutaneous; Crohn Disease; Behcet Syndrome; Uveitis; Colitis, Ulcerative; Arthritis, Psoriatic; Arthritis, Juvenile; Lupus Nephritis; Glomerulonephritis, Membranous; Non-radiographic axial spondyloarthritis; Spondylitis, Ankylosing; Sjogren's Syndrome; Arthritis, Rheumatoid; Inflammatory Bowel Diseases; Immunoglobulin G4-Related Disease; Myositis; Renal Insufficiency | Details |
| Deuterated Ruxolitinib | CTP-543; C-21543 phosphate; CTP-543 phosphate | Approved | Concert | LEQSELVI | United States | Alopecia Areata | Sun Pharmaceutical Industries Ltd | 2024-07-25 | Alopecia Areata; Renal Insufficiency; Hepatic Insufficiency | Details |
| Peficitinib | ASP-015K; JNJ-54781532 | Approved | Astellas Pharma Inc | Smyraf | Japan | Arthritis, Rheumatoid | Astellas Pharma Inc | 2019-03-29 | Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative | Details |
| Momelotinib Dihydrochloride | CYT-387; GS-0387; GSK-3070785 | Approved | Gilead Sciences Inc, Cytopia Pty Ltd | Ojjaara, Omjjara | United States | Primary Myelofibrosis; Anemia | Glaxosmithkline Llc, Glaxosmithkline Plc | 2023-09-15 | Polycythemia Vera; Anemia; Neoplasms; Myeloproliferative Disorders; Pancreatic Intraductal Neoplasms; Primary Myelofibrosis; Carcinoma, Pancreatic Ductal; Splenomegaly; Thrombocythemia, Essential; Carcinoma, Non-Small-Cell Lung | Details |
| Abrocitinib | PF-4965842; PF-04965842 | Approved | Pfizer Inc | Cibinqo, CIBINQO, 希必可 | United Kingdom | Dermatitis, Atopic | Pfizer Inc | 2021-09-09 | Food Hypersensitivity; Plaque psoriasis; Hypersensitivity; Dermatitis, Atopic; Eczema; Skin Diseases, Genetic; Hypersensitivity, Immediate; Hepatic Insufficiency; Prurigo; Post-Acute COVID-19 Syndrome; Granuloma Annulare; Pruritus; Prurigo Nodularis; Immune System Diseases; Genetic Diseases, Inborn; Skin Diseases; Skin Diseases, Eczematous; Dermatitis; Fatigue; Sarcoidosis; Renal Insufficiency | Details |
| Tofacitinib Citrate | CP-690550; AC-1101; IMG 003; CGB-500; CP-690550-10; CKD-374; Tasocitinib; BI-764524 | Approved | Pfizer Inc | Jakvinus, Xeljanz, 尚杰 | United States | Arthritis, Rheumatoid | Pf Prism Cv | 2012-11-06 | Inflammation; Arthritis, Juvenile; Lung Diseases, Interstitial; Dermatitis; Psoriasis; Lupus Erythematosus, Systemic; Granuloma Annulare; Colitis, Ulcerative; Arthritis, Psoriatic; Sarcoidosis, Pulmonary; Hepatic Insufficiency; Granulomatous Disease, Chronic; Dry Eye Syndromes; Lymphoma, T-Cell, Cutaneous; Uveitis; Hidradenitis Suppurativa; Crohn Disease; Kidney Failure, Chronic; Plaque psoriasis; Dermatitis, Atopic; Amyotrophic Lateral Sclerosis; Eczema; Vitiligo; Lupus Erythematosus, Discoid; Keratoconjunctivitis Sicca; Alopecia; Non-radiographic axial spondyloarthritis; Alopecia Areata; Pneumonia; Gastrointestinal Diseases; Renal Insufficiency; Depression; Scleritis; Down Syndrome; Dermatomyositis; Rejection of renal transplantation; Sacroiliitis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Sjogren's Syndrome; Coronavirus Disease 2019 (COVID-19); Glioblastoma; Scleroderma, Systemic; Sarcoidosis; Lupus Erythematosus, Cutaneous; Spondylitis | Details |
| Golidocitinib | DZD-4205; AZD-4205; NC-0322 | Approved | Astrazeneca Plc, Dizal (Jiangsu) Pharmaceutical Co Ltd | 高瑞哲 | Mainland China | Lymphoma, T-Cell, Peripheral | Dizal (Jiangsu) Pharmaceutical Co Ltd | 2024-06-18 | Lymphoma, T-Cell, Peripheral; Lymphoma, T-Cell, Cutaneous; Carcinoma, Non-Small-Cell Lung | Details |
| Upadacitinib | ABT-494 | Approved | Abbott Laboratories | RINVOQ LQ, 瑞福, Rinvoq, Rinvoq Lq | United States | Arthritis, Rheumatoid | Abbvie Inc | 2019-08-16 | Lung Diseases, Interstitial; Vitiligo; Dermatitis, Atopic; Crohn Disease; Hidradenitis Suppurativa; Arthritis, Psoriatic; Colitis, Ulcerative; Takayasu Arteritis; Lupus Erythematosus, Systemic; Blepharitis; Non-radiographic axial spondyloarthritis; Arthritis, Juvenile; Sleep Wake Disorders; Spondylitis, Ankylosing; Spondylarthritis; Arthritis, Rheumatoid; Polyarticular Juvenile Idiopathic Arthritis; Giant Cell Arteritis; Alopecia Areata | Details |
| Baricitinib | LY-3009104; INCB-028050 | Approved | Incyte Corp | 艾乐明, Olumiant | EU | Arthritis, Rheumatoid | Eli Lilly Nederland BV | 2017-02-13 | Diabetic Nephropathies; Pyoderma; Post-Acute COVID-19 Syndrome; Severe Acute Respiratory Syndrome; Lupus Erythematosus, Systemic; Psoriasis; Cholangitis, Sclerosing; Coronavirus Infections; Anhedonia; Skin Ulcer; Polymyalgia Rheumatica; Hepatic Insufficiency; Wounds and Injuries; Aicardi Goutieres syndrome; Renal Insufficiency, Chronic; Skin Diseases, Papulosquamous; Lichen Planus, Oral; Acute Lung Injury; Dermatitis, Atopic; Vitiligo; Coronavirus Disease 2019 (COVID-19); HIV Infections; Diabetes Mellitus, Type 1; Pyoderma Gangrenosum; Alopecia Areata; Cerebral Hemorrhage; Dermatomyositis; Myositis; Nephritis; Depression; Infections; Arthritis, Rheumatoid; Pemphigoid, Benign Mucous Membrane; Graft vs Host Disease; Conjunctivitis; Arthritis, Juvenile; Skin Diseases; Liver Diseases; Lupus Nephritis | Details |
| Ruxolitinib Phosphate | INC-424; INCB-424; INCB-18424; RUX; INCB 018424 phosphate; INCB-018424 | Approved | Incyte Corp | OPZELURA, Jakavi, Jakafi | United States | Primary Myelofibrosis | Incyte Corp | 2011-11-16 | Pancytopenia; Lymphoma; Hyperplasia; Leukemia, Myeloid, Chronic-Phase; Lichen Planus; Prurigo; Hepatomegaly; Primary Myelofibrosis; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Leukemia, Myeloid, Acute; Coronavirus Infections; Anemia, Aplastic; Prostatic Neoplasms; Thrombocytosis; Carcinoma, Intraductal, Noninfiltrating; Ectodermal Dysplasia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Breast Neoplasms; Vitiligo; Exanthema; Leukemia, T-Cell; Eczema; Leukemia, Lymphocytic, Chronic, B-Cell; Dermatitis, Atopic; Myelodysplastic-Myeloproliferative Diseases; Carcinoma, Non-Small-Cell Lung; Thrombocythemia, Essential; Psoriasis; Lymphohistiocytosis, Hemophagocytic; Lichen Sclerosus et Atrophicus; Hidradenitis Suppurativa; Carcinoma, Squamous Cell; Cachexia; Lymphoma, Non-Hodgkin; Splenomegaly; Polycythemia Vera; Pancreatic Neoplasms; Myelodysplastic Syndromes; Arthritis, Rheumatoid; Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19); Alopecia Areata; Squamous Cell Carcinoma of Head and Neck; L | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| PG-011 | PG-011 | Phase 3 Clinical | Prime Gene Therapeutics Co Ltd | Radiodermatitis; Epidermolysis Bullosa; Dermatitis; Rhinitis, Allergic; Prurigo; Eye Diseases; Dermatitis, Atopic; Vitiligo | Details |
| Povorcitinib | INCB-54707; INCB54707; INCB054707; INCB-054707 | Phase 3 Clinical | Incyte Corp | Pruritus; Renal Insufficiency; Chronic Urticaria; Kidney Diseases; Prurigo Nodularis; Urticaria; Asthma; Hidradenitis Suppurativa; Angioedema; Vitiligo | Details |
| Brepocitinib | PF-06700841-15; PF-6700841; PF-841; PF-06700841 | Phase 3 Clinical | Pfizer Inc | Colitis, Ulcerative; Crohn Disease; Vitiligo; Dermatitis, Atopic; Plaque psoriasis; Panuveitis; Hidradenitis Suppurativa; Uveitis; Uveitis, Posterior; Alopecia; Arthritis, Psoriatic; Psoriasis; Lupus Erythematosus, Systemic; Alopecia Areata; Renal Insufficiency; Uveitis, Intermediate; Dermatomyositis | Details |
| WXFL-10203614 | WXFL-10203614; [14C]WXFL10203614 | Phase 3 Clinical | Wuxi Fuxin Pharmaceutical Research And Development Co Ltd, Wuxi Apptec Co Ltd | Arthritis, Rheumatoid; Colitis, Ulcerative; Dermatitis, Atopic; Crohn Disease | Details |
| TLL-018 | TLL-018 | Phase 3 Clinical | Tll Pharmaceutical Llc | Arthritis, Rheumatoid; Chronic Urticaria; Lupus Erythematosus, Systemic; Psoriasis; Colitis, Ulcerative; Urticaria; Plaque psoriasis; Dermatitis, Atopic | Details |
| Tinengotinib | TT-00420; TT 00420; TT00420 | Phase 3 Clinical | TransThera Sciences (Nanjing) Inc | Biliary Tract Neoplasms; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Cholangiocarcinoma; Sarcoma; Prostatic Neoplasms; Gallbladder Neoplasms; Thyroid Neoplasms | Details |
| LW-402 | [14C]LW402; LW-402 | Phase 3 Clinical | Shanghai Longwood Biopharmaceuticals Co Ltd | Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Dermatitis, Atopic; Vitiligo | Details |
| VC-005 | VC-005 | Phase 3 Clinical | Jiangsu Vcare Pharmatech Co Ltd | Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Joint Diseases; Colitis, Ulcerative; Dermatitis, Atopic; Eczema; Crohn Disease; Vitiligo | Details |
| ICP-332 | ICP-332 | Phase 3 Clinical | InnoCare Pharma Ltd | Psoriasis; Vitiligo; Dermatitis, Atopic | Details |
| LNK-01001 | LNK-01001; LNK01001; LNK-001; LNK001; LNK-207; EQ-121 | Phase 3 Clinical | Lynk Pharmaceutical (Hangzhou) Co Ltd | Spondylitis, Ankylosing; Arthritis, Rheumatoid; Dermatitis, Atopic | Details |
| Itacitinib | INCB-039110-adipate; INCB-39110; INCB-039110; IBI-377 | Phase 3 Clinical | Incyte Corp | Leukemia, Myeloid, Acute; Multiple Myeloma; Sarcoma; Hemic and Lymphatic Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thrombocytosis; Breast Neoplasms; Leukemia, B-Cell; Primary Myelofibrosis; Colitis, Ulcerative; Asthma; Colorectal Neoplasms; Lymphoma; Liposarcoma; Lymphoma, Non-Hodgkin; Lung Neoplasms; Endometrial Neoplasms; Lymphohistiocytosis, Hemophagocytic; Leukemia, Prolymphocytic, T-Cell; Carcinoma, Hepatocellular; Liposarcoma, Myxoid; Plaque psoriasis; Neoplasm Metastasis; Melanoma; Carcinoma, Non-Small-Cell Lung; Myelodysplastic-Myeloproliferative Diseases; Graft vs Host Disease; Leiomyosarcoma; Lymphoma, B-Cell; Chondrosarcoma; Bronchiolitis Obliterans; Solid tumours; Cytokine Release Syndrome; Head and Neck Neoplasms; Leukemia, Myelogenous, Chronic; Leukemia; Polycythemia Vera; Carcinoma, Renal Cell; Pruritus; Hematologic Neoplasms; Hodgkin Disease; Myelodysplastic Syndromes; Neoplasms; Lymphoma, Large B-Cell, Diffuse; Arthritis, Rheumatoid; Pancreatic Neoplasms; Myeloproliferative Di | Details |
| WXSH-0150 | WXSH-0150; TUL-01101 | Phase 2 Clinical | Zhuhai United Laboratories Co Ltd | Arthritis, Rheumatoid; Dermatitis, Atopic | Details |
| Elsubrutinib/Upadacitinib | ABBV-599 | Phase 2 Clinical | Abbvie Inc | Arthritis, Rheumatoid; Lupus Erythematosus, Systemic | Details |
| NS-229 | NS-229 | Phase 2 Clinical | Neurosearch As | Eosinophilic Granulomatosis With Polyangiitis; Epilepsy | Details |
| TDM-180935 | TDM-180935 | Phase 2 Clinical | Jiaxing TechnoDerma Medicines Inc | Dermatitis, Atopic | Details |
| AC-201 | AC-201 | Phase 2 Clinical | Accro Bioscience (Suzhou) Co Ltd | Psoriasis; Lupus Erythematosus, Systemic; Uveitis | Details |
| VVN-461 | VVN461e; VVN-461-e; VVN-461 | Phase 2 Clinical | VivaVision Biotech Inc | Uveitis, Anterior; Uveitis; Inflammation; Postoperative inflammation | Details |
| Fingolimod/Tofacitinib | FMX-114 | Phase 2 Clinical | Vyne Therapeutics Inc | Dermatitis, Atopic | Details |
| QY201 | QY-201; QY201 | Phase 2 Clinical | E-nitiate Biopharmaceuticals (Hangzhou) Co Ltd | Alopecia Areata; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Prurigo; Dermatitis, Atopic | Details |
| AZD-4604 | AZD-4604 | Phase 2 Clinical | Astrazeneca Plc | Asthma | Details |
| Lepzacitinib | Phase 2 Clinical | Aclaris Therapeutics Inc | Dermatitis, Atopic | Details | |
| CS-12192 | CS12192 | Phase 1 Clinical | Shenzhen Chipscreen Biosciences Co Ltd | Enteritis; Alopecia Areata; Autoimmune Diseases; Graft vs Host Disease; Multiple Sclerosis; Lupus Erythematosus, Systemic; Dermatitis, Atopic | Details |
| FZJ-003 | FZJ-003 | Phase 1 Clinical | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd | Arthritis, Rheumatoid; Dermatitis, Atopic | Details |
| Frevecitinib | VR-588; KN-002; KN-002 (Kinaset Therapeutics/Vectura) | Phase 1 Clinical | Vectura Ltd | Asthma; Pulmonary Disease, Chronic Obstructive | Details |
| GLPG-3121 | GLPG-3121 | Phase 1 Clinical | Galapagos Nv | Details | |
| tofacitinib (3S Bio) | SSS-32 | Phase 1 Clinical | 3sbio Inc | Arthritis, Rheumatoid | Details |
| LP-0184 | LP-0184 | Phase 1 Clinical | Leo Pharma A/S | Dermatitis, Atopic | Details |
| Tofacitinib(Biora Therapeutics) | BT-600; PGN-600 | Phase 1 Clinical | Progenity Inc | Colitis, Ulcerative | Details |
| Ruxolitinib (Taro Pharmaceuticals) | Phase 1 Clinical | Taro Pharmaceuticals Usa Inc | Dermatitis, Atopic | Details | |
| Tofacitinib citrate (TWi Biotechnology) | AC-1101; IMG 003 | Phase 1 Clinical | Twi Biotechnology Inc | Granuloma Annulare | Details |
| GDC-0214 | RG-6151; GDC-0214 | Phase 1 Clinical | Genentech Inc | Asthma | Details |
| BHV-8000 | TLL-041; TLL041 | Phase 1 Clinical | Hangzhou Highlightll Pharmaceutical Co Ltd | Alzheimer Disease; Parkinson Disease; Central Nervous System Diseases; Amyotrophic Lateral Sclerosis | Details |
| QY-211 | QY211; QY-211 | Phase 1 Clinical | E-nitiate Biopharmaceuticals (Hangzhou) Co Ltd | Psoriasis; Dermatitis, Atopic; Eczema; Vitiligo | Details |
| AQ-280 | AQ-280 | Phase 1 Clinical | Aqilion AB | Eosinophilic Esophagitis | Details |
| PG-018 | PG-018 | Phase 1 Clinical | Prime Gene Therapeutics Co Ltd | Nephrosis; Glomerulonephritis, Membranous | Details |
| MAX-40070 | MAX-40070 | Phase 1 Clinical | Maxinovel Pty Ltd | Alopecia Areata | Details |
| H-018 | H018; H-018 | Phase 1 Clinical | Jiangsu Carephar Pharmaceutical Co Ltd, Nanjing Shenzhou Jiamei Pharmaceutical Co Ltd | Arthritis, Rheumatoid; Dermatitis, Atopic; Vitiligo | Details |
| TT-00420/Atezolizumab | Phase 1 Clinical | TransThera Sciences (Nanjing) Inc | Gastrointestinal Neoplasms | Details | |
| LBG-1600M | Phase 1 Clinical | Suzhou Longbotai Pharmaceutical Co Ltd | Dermatitis, Atopic | Details | |
| LNK-01002 | LNK01002 | Phase 1 Clinical | Lynk Pharmaceutical (Hangzhou) Co Ltd | Hematologic Neoplasms; Polycythemia Vera; Myeloproliferative Disorders; Primary Myelofibrosis; Leukemia, Myeloid, Acute; Thrombocythemia, Essential | Details |
| NIP-046 | NIP-046 | Phase 1 Clinical | National Institutes Of Pharmaceutical Research And Development Co Ltd | Arthritis, Rheumatoid; Chronic Urticaria | Details |
| Tofacitinib controlled release (Triastek) | T-21; T21 | Clinical | Triastek Inc | Colitis, Ulcerative | Details |
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