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| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| JA1-H5547 | Human | Human JAK1 Protein, His Tag |  |
|
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Peficitinib | ASP-015K; JNJ-54781532 | Approved | Astellas Pharma Inc | Smyraf | Japan | Arthritis, Rheumatoid | Astellas Pharma Inc | 2019-03-29 | Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative | Details |
| Filgotinib Maleate | G-146034-101; GS-6034; G-146034; GLPG-0634 | Approved | Galapagos Nv | Jyseleca | EU | Colitis, Ulcerative | Gilead Sciences Kk | 2020-09-24 | Non-radiographic axial spondyloarthritis; Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Lupus Erythematosus, Cutaneous; Spondylitis, Ankylosing; Sjogren's Syndrome; Kidney Diseases; Lupus Nephritis; Glomerulonephritis, Membranous; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Crohn Disease | Details |
| Abrocitinib | PF-4965842; PF-04965842 | Approved | Pfizer Inc | 希必可, Cibinqo | United Kingdom | Dermatitis, Atopic | Pfizer Inc | 2021-09-09 | Psoriasis; Dermatitis, Atopic; Eczema; Skin Diseases, Genetic; Hypersensitivity; Hypersensitivity, Immediate; Prurigo; Hepatic Insufficiency; Food Hypersensitivity; Pruritus; Granuloma Annulare; Genetic Diseases, Inborn; Skin Diseases, Eczematous; Immune System Diseases; Skin Diseases; Dermatitis; Kidney Diseases; Sarcoidosis | Details |
| Upadacitinib | ABT-494 | Approved | Abbvie Inc | Rinvoq | United States | Arthritis, Rheumatoid | Abbvie Inc | 2019-08-16 | Non-radiographic axial spondyloarthritis; Giant Cell Arteritis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Spondylarthritis; Arthritis, Juvenile; Lupus Erythematosus, Systemic; Takayasu Arteritis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Dermatitis, Atopic; Crohn Disease; Vitiligo | Details |
| Ruxolitinib Phosphate | INCB-018424; INC-424; INCB-424; INCB-18424 | Approved | Incyte Corp | Jakafi, Jakavi, OPZELURA | United States | Primary Myelofibrosis | Incyte Corp | 2011-11-16 | Coronavirus Infections; Carcinoma, Squamous Cell; Lymphoma; Lichen Planus; Hyperplasia; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Hepatomegaly; Leukemia, Myeloid, Chronic-Phase; Primary Myelofibrosis; Lymphohistiocytosis, Hemophagocytic; Carcinoma, Intraductal, Noninfiltrating; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ectodermal Dysplasia; Breast Neoplasms; Leukemia, Neutrophilic, Chronic; Psoriasis; Prostatic Neoplasms; Thrombocytosis; Hidradenitis Suppurativa; Cachexia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Lichen Sclerosus et Atrophicus; Splenomegaly; Thrombocythemia, Essential; Vitiligo; Dermatitis, Atopic; Leukemia, Lymphocytic, Chronic, B-Cell; Carcinoma, Non-Small-Cell Lung; Eczema; Leukemia, Large Granular Lymphocytic; Leukemia, T-Cell; Myelodysplastic-Myeloproliferative Diseases; Cytokine Release Syndrome; Arthritis, Rheumatoid; Leukemia, Myelomonocytic, Chronic; Graft vs Host Disease; Myeloproliferative Disorders; Alopecia Areata; Lupus Erythematosus, Discoid; Squamou | Details |
| Baricitinib | LY-3009104; INCB-028050 | Approved | Incyte Corp | 艾乐明, Olumiant | EU | Arthritis, Rheumatoid | Eli Lilly Nederland BV | 2017-02-13 | Liver Diseases; Dermatitis, Atopic; Renal Insufficiency, Chronic; Wounds and Injuries; Skin Diseases, Papulosquamous; Skin Ulcer; Hepatic Insufficiency; Diabetic Nephropathies; Severe Acute Respiratory Syndrome; Pyoderma; Coronavirus Infections; Psoriasis; Lupus Erythematosus, Systemic; Lupus Nephritis; Polymyalgia Rheumatica; Conjunctivitis; Infections; Skin Diseases; Arthritis, Juvenile; Pemphigoid, Benign Mucous Membrane; Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19); Arthritis, Rheumatoid; Nephritis; Dermatomyositis; Pyoderma Gangrenosum; Myositis; Alopecia Areata; HIV Infections; Liver Cirrhosis, Biliary; Diabetes Mellitus, Type 1 | Details |
| Tofacitinib Citrate | Tasocitinib; BI-764524; CP-690550; AC-1101; IMG 003; CP-690550-10; CKD-374; SSS-32 | Approved | Pfizer Inc | Jakvinus, Xeljanz, 尚杰 | United States | Arthritis, Rheumatoid | Pf Prism Cv | 2012-11-06 | Uveitis; Arthritis, Juvenile; Lung Diseases, Interstitial; Lung Diseases; Psoriasis; Lupus Erythematosus, Systemic; Granuloma Annulare; Arthritis, Psoriatic; Colitis, Ulcerative; Hepatic Insufficiency; Sarcoidosis, Pulmonary; Dry Eye Syndromes; Inflammation; Granulomatous Disease, Chronic; Hidradenitis Suppurativa; Crohn Disease; Diabetic Retinopathy; Vitiligo; Dermatitis, Atopic; Plaque psoriasis; Eczema; Arthritis, Rheumatoid; Rejection of renal transplantation; Keratoconjunctivitis Sicca; Alopecia Areata; Scleritis; Lupus Erythematosus, Discoid; Gastrointestinal Diseases; Down Syndrome; Sacroiliitis; Depression; Dermatomyositis; Alopecia; Spondylitis, Ankylosing; Scleroderma, Systemic; Coronavirus Disease 2019 (COVID-19); Lupus Erythematosus, Cutaneous; Sjogren's Syndrome; Sarcoidosis; Kidney Diseases; Spondylitis; Glioblastoma | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Fingolimod/Tofacitinib | FMX-114 | Phase 2 Clinical | Vyne Therapeutics Inc | Dermatitis, Atopic | Details |
| TT-00420/Atezolizumab | Phase 1 Clinical | TransThera Sciences (Nanjing) Inc | Gastrointestinal Neoplasms | Details | |
| MAX-40070 | MAX-40070 | Phase 1 Clinical | Maxinovel Pty Ltd | Alopecia Areata | Details |
| FZJ-003 | FZJ-003 | Phase 1 Clinical | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd | Arthritis, Rheumatoid; Dermatitis, Atopic | Details |
| Elsubrutinib/Upadacitinib | ABBV-599 | Phase 1 Clinical | Abbvie Inc | Arthritis, Rheumatoid; Lupus Erythematosus, Systemic | Details |
| LW-402 | LW-402 | Phase 2 Clinical | Shanghai Longwood Biopharmaceuticals Co Ltd | Arthritis, Rheumatoid; Dermatitis, Atopic | Details |
| GLPG-3121 | GLPG-3121 | Phase 1 Clinical | Galapagos Nv | Details | |
| LBG-1600M | Phase 1 Clinical | Suzhou Longbotai Pharmaceutical Co Ltd | Dermatitis, Atopic | Details | |
| H-018 | H018; H-018 | Phase 1 Clinical | Jiangsu Carephar Pharmaceutical Co Ltd, Nanjing Shenzhou Jiamei Pharmaceutical Co Ltd | Arthritis, Rheumatoid | Details |
| TLL-018 | TLL-018 | Phase 2 Clinical | Tll Pharmaceutical Llc | Chronic Urticaria; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Urticaria | Details |
| NIP-046 | NIP-046 | Phase 1 Clinical | National Institutes Of Pharmaceutical Research And Development Co Ltd | Arthritis, Rheumatoid | Details |
| LNK-01002 | LNK01002 | Phase 1 Clinical | Lynk Pharmaceutical (Hangzhou) Co Ltd | Hematologic Neoplasms; Myeloproliferative Disorders; Primary Myelofibrosis; Leukemia, Myeloid, Acute | Details |
| PG-011 | PG-011 | Phase 2 Clinical | Prime Gene Therapeutics Co Ltd | Epidermolysis Bullosa; Rhinitis, Allergic; Prurigo; Eye Diseases; Dermatitis, Atopic | Details |
| QY201 | QY-201; QY201 | Phase 2 Clinical | E-nitiate Biopharmaceuticals (Hangzhou) Co Ltd | Alopecia Areata; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Dermatitis, Atopic | Details |
| GDC-0214 | RG-6151; GDC-0214 | Phase 1 Clinical | Genentech Inc | Asthma | Details |
| WXFL-10203614 | WXFL-10203614 | Phase 2 Clinical | Wuxi Fuxin Pharmaceutical Research And Development Co Ltd, Wuxi Apptec Co Ltd | Arthritis, Rheumatoid | Details |
| AQ-280 | AQ-280 | Phase 1 Clinical | Aqilion AB | Eosinophilic Esophagitis | Details |
| Tinengotinib | TT-00420 | Phase 2 Clinical | TransThera Sciences (Nanjing) Inc | Solid tumours; Biliary Tract Neoplasms; Stomach Neoplasms; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Prostatic Neoplasms; Sarcoma; Thyroid Neoplasms; Gallbladder Neoplasms | Details |
| VC-005 | VC-005 | Phase 1 Clinical | Jiangsu Vcare Pharmatech Co Ltd | Inflammatory Bowel Diseases; Joint Diseases; Colitis, Ulcerative; Crohn Disease; Vitiligo; Dermatitis, Atopic | Details |
| Golidocitinib | NC-0322; AZD-4205; DZD-4205 | Phase 2 Clinical | Astrazeneca Plc, Dizal (Jiangsu) Pharmaceutical Co Ltd | Lymphoma, T-Cell, Peripheral; Lymphoma, T-Cell, Cutaneous; Carcinoma, Non-Small-Cell Lung | Details |
| WXSH-0150 | WXSH-0150; TUL-01101 | Phase 1 Clinical | Zhuhai United Laboratories Co Ltd | Arthritis, Rheumatoid; Dermatitis, Atopic | Details |
| Povorcitinib | INCB-54707; INCB54707; INCB054707; INCB-054707 | Phase 3 Clinical | Incyte Corp | Renal Insufficiency; Kidney Diseases; Prurigo; Hidradenitis Suppurativa; Vitiligo | Details |
| Brepocitinib | PF-06700841-15; PF-6700841; PF-841; PF-06700841 | Phase 3 Clinical | Pfizer Inc | Alopecia; Dermatomyositis; Alopecia Areata; Kidney Diseases; Lupus Erythematosus, Systemic; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Vitiligo; Dermatitis, Atopic; Crohn Disease | Details |
| LNK-01001 | LNK01001; LNK-01001 | Phase 2 Clinical | Lynk Pharmaceutical (Hangzhou) Co Ltd | Spondylitis, Ankylosing; Arthritis, Rheumatoid; Dermatitis, Atopic | Details |
| ATI-1777 | Phase 2 Clinical | Aclaris Therapeutics Inc | Dermatitis, Atopic | Details | |
| Ivarmacitinib sulfate | SHR-0302; ARQ-252 | Phase 3 Clinical | Jiangsu Hengrui Medicine Co Ltd | Non-radiographic axial spondyloarthritis; Alopecia Areata; Arthritis, Rheumatoid; Spondylarthritis; Spondylitis, Ankylosing; Colitis, Ulcerative; Arthritis, Psoriatic; Hepatic Insufficiency; Dermatitis, Atopic; Vitiligo; Crohn Disease; Eczema | Details |
| Itacitinib | INCB-039110-adipate; INCB-39110; INCB-039110; IBI-377 | Phase 3 Clinical | Incyte Corp | Lymphoma; Psoriasis; Hemic and Lymphatic Diseases; Thrombocytosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Breast Neoplasms; Sarcoma; Colitis, Ulcerative; Primary Myelofibrosis; Asthma; Colorectal Neoplasms; Lymphohistiocytosis, Hemophagocytic; Sarcoma, Synovial; Lung Neoplasms; Lymphoma, Non-Hodgkin; Leukemia, Myeloid, Acute; Endometrial Neoplasms; Myelodysplastic-Myeloproliferative Diseases; Neoplasm Metastasis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liposarcoma, Myxoid; Melanoma; Carcinoma, Renal Cell; Cytokine Release Syndrome; Leukemia; Lymphoma, B-Cell; Bronchiolitis Obliterans; Solid tumours; Head and Neck Neoplasms; Chondrosarcoma; Leiomyosarcoma; Polycythemia Vera; Pruritus; Hematologic Neoplasms; Arthritis, Rheumatoid; Graft vs Host Disease; Hodgkin Disease; Neoplasms; Myelodysplastic Syndromes; Myeloproliferative Disorders; Leukemia, Myelomonocytic, Chronic; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Liposarcoma | Details |
| Deuterated Ruxolitinib | CTP-543 | Phase 3 Clinical | Concert | Alopecia Areata; Kidney Diseases; Hepatic Insufficiency | Details |
| VVN-461 | VVN461e; VVN-461 | Phase 1 Clinical | VivaVision Biotech Inc | Uveitis, Anterior; Uveitis | Details |
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