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Envelope protein

Brief Information

Name:Recombinant envelope protein
Target Synonym:env,Submitted name: Recombinant envelope protein,Viral Envelope Proteins
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Approved

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Part of Bioactivity data

 Envelope protein SPR

Anti-E(DENV) Antibody EDE2 A11 captured on Protein G-Series S sensor chip can bind DENV2 (strain Thailand/16681/1984) Envelope Protein, His Tag (Cat. No. ENN-D5243) with an affinity constant of 58.4 nM as determined in a SPR assay (Biacore 8K) (QC tested).

Envelope protein MALS images

The purity of DENV2 (strain Thailand/16681/1984) Envelope Protein, His Tag (Cat. No. ENN-D5244) is more than 85% and the molecular weight of this protein is around 90-110 kDa verified by SEC-MALS.

Synonym Name

Envelope protein,Env polyprotein,Envelope glycoprotein,env


The SARS-CoV-2 is composed of a double-layered lipid envelope, including Spike glycoprotein (S), Envelope protein (E), Membrane glycoprotein (M), and Nucleocapsid protein (Nucleocapsid protein, N). Among them, The amino acid sequence of the SARS-CoV-2 envelope protein is 95% identical of the SARS envelope protein.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Tecovirimat ST-246; SIGA-246 Approved Siga Technologies Inc Tpoxx United States Smallpox Siga Technologies Inc 2018-07-13 Smallpox; Cowpox; Vaccinia; Poxviridae Infections; Monkeypox Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Targeting HIV-1 Env gp140 antibodies Phase 2 Clinical National Institute Of Allergy And Infectious Diseases (Niaid) HIV Infections Details
PGDM-1400 PGDM-1400 Phase 2 Clinical International Aids Vaccine Initiative HIV Infections; Acquired Immunodeficiency Syndrome; Retroviridae Infections; Sexually Transmitted Diseases, Viral Details
Temelimab GNN-001; GENHP-01; GNbAC-1 Phase 2 Clinical Geneuro Sa Diabetes Mellitus, Type 1; Multiple Sclerosis, Relapsing-Remitting; Coronavirus Disease 2019 (COVID-19); Multiple Sclerosis Details

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