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CD5L

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Synonym Name

CD5L,API6,CT-2,SP-alpha,IgM-associated peptide

Background

CD5 antigen-like (CD5L) is also known as CT-2, IgM-associated peptide, SP-alpha, API6, is a secreted soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. CD5L is expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues. CD5L may play a role in the regulation of the immune system. CD5L seems to play a role as an inhibitor of apoptosis. CD5L associates with IgM.

Clinical and Translational Updates

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