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NKG2C & CD94

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Cat. No. Species Product Description Structure Purity Feature
NC4-H82E3 Human Biotinylated Human NKG2C&CD94 Protein, His,Avitag™ (MALS verified)
NC4-H5258 Human Human NKG2C&CD94 Protein, Fc Tag
ACRO Quality

Part of Bioactivity data


HLA-E*01:03 HLA-A leader3-11 Tetramer-VMAPRTLVL-PE immobilized on CM5 Chip can bind Human NKG2C&CD94 Protein, His,Avitag™ (Cat. No. NC4-H82E3) with an affinity constant of 63.7 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Human NKG2C&CD94, Fc TagHuman NKG2C&CD94, Fc Tag (Cat. No. NC4-H5258) ELISA bioactivity

Immobilized Human NKG2C&CD94, Fc Tag (Cat. No. NC4-H5258) at 5 μg/mL (100 μL/well) can bind HLA-E*01:03 HLA-A leader3-11 Tetramer-VMAPRTLVL-PE,TS-ME01-1 (QC tested).

NKG2C & CD94 Molecule Synonym Name

NKG2C & CD94

NKG2C & CD94 Molecule Background

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2C/CD159c is used as a receptor for NK cells and some cytotoxic T cells to recognize MHC class I HLA-E molecules. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

NKG2C & CD94 References

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