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L-Selectin

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ACRO Quality

Synonym Name

SELL,CD62L,LNHR,LYAM1,L-selectin,LAM-1,LECAM1,TQ1,gp90-MEL

Background

CD62 antigen-like family member L (CD62L) is also known as L-selectin (SELL), Leukocyte adhesion molecule 1 (LAM-1), Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1 (LECAM1), Lymph node homing receptor, which belongs to the selectin/LECAM family. As cell surface adhesion protein, CD62L mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. CD62L / L-selectin promotes initial tethering and rolling of leukocytes in endothelia.

Clinical and Translational Updates

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