| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| ILC-H5257 | Human | Human IL-17 RA & IL-17 RC Heterodimer Protein, Fc Tag&Fc Tag |  |
|
|
Human IL17RA & IL17RC Protein, Fc Tag&Fc Tag (Cat. No. ILC-H5257) captured on CM5 chip via anti-human IgG Fc antibody can bind Human IL-17A&IL-17F Heterodimer Protein, Twin Strep&His Tag (Cat. No. ILF-H52W6) with an affinity constant of 50.8 pM as determined in a SPR assay (Biacore 8K) (Routinely tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Brodalumab | IL-17R mAb; MEDI-6365; KHK-4827; AMG-827 | Approved | Amgen Inc | Siliq, Lumicef, Kyntheum, 立美芙 | Mainland China | Plaque psoriasis | Kyowa Kirin | 2016-07-04 | Arthritis, Rheumatoid; Spondylitis, Ankylosing; Scleroderma, Systemic; Psoriasis; Asthma; Arthritis, Psoriatic; Crohn Disease; Plaque psoriasis | Details |
| Brodalumab | IL-17R mAb; MEDI-6365; KHK-4827; AMG-827 | Approved | Amgen Inc | Siliq, Lumicef, Kyntheum, 立美芙 | Mainland China | Plaque psoriasis | Kyowa Kirin | 2016-07-04 | Arthritis, Rheumatoid; Spondylitis, Ankylosing; Scleroderma, Systemic; Psoriasis; Asthma; Arthritis, Psoriatic; Crohn Disease; Plaque psoriasis | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| LY-3114062 | LY3114062; LY-3114062 | Phase 1 Clinical | Eli Lilly And Company | Arthritis | Details |
| S-011806 | S-011806 | Phase 1 Clinical | Psoriasis | Details | |
| XCUR-17 | XCUR-17 | Phase 1 Clinical | Exicure | Psoriasis | Details |
| LY-3114062 | LY3114062; LY-3114062 | Phase 1 Clinical | Eli Lilly And Company | Arthritis | Details |
| S-011806 | S-011806 | Phase 1 Clinical | Psoriasis | Details | |
| XCUR-17 | XCUR-17 | Phase 1 Clinical | Exicure | Psoriasis | Details |
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