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IFN-alpha 2b

Brief Information

Name:Interferon alpha-2
Target Synonym:IFNA2B,IFNA2C,LeIF A,Interferon alpha-2,IFN-alpha-2,IFNA2,Interferon Alpha 2,Alpha-2a Interferon,Interferon Alpha 2b,Interferon Alpha A,Interferon Alpha 2a,Interferon Alpha-A,IFN-AlphaA,IFNA2A,INFA2,IFNA
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
IFB-H5253 Human Human IFN-alpha 2b Protein, Fc Tag (MALS verified)
ACRO Quality

Part of Bioactivity data

 IFN-alpha 2b SPR

Human IFN-alpha 2b (K46R), Fc Tag (Cat. No. IFB-H5253) immobilized on CM5 Chip can bind Human IFNAR2, His Tag (Cat. No. IF2-H5224) with an affinity constant of 0.257 μM as determined in SPR assay (Biacore T200) (Routinely tested).

IFN-alpha 2b MALS images

The purity of Human IFN-alpha 2b, Fc Tag (Cat. No. IFB-H5253) is more than 90% and the molecular weight of this protein is around 95-105 kDa verified by SEC-MALS.

Synonym Name

IFN-alpha 2b,IFNA2B,IFN-alpha 2 (alpha 2b),interferon alpha 2b


IFN-alpha is a cytokine that has an immunomodulatory function. It plays an important role not only in antiviral activity but also in several physiologic functions, such as activation of dendritic cells and accelerated expression of major histocompatibility complex I and II molecules that may cause increased antigen presentation. Variants of human leukocyte interferon alpha 2 (IFN-alpha 2a, alpha 2b, and alpha 2c) differ from each other by changes in their coding regions at nucleotide positions 137 and 170. IFN-alpha 2b (IFNα-2b) is an important cytokine and used for antiviral and anticancer treatment.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Nadofaragene firadenovec SCH-721015 Approved Schering - Plough Sa, Fkd Therapies Adstiladrin United States Urinary Bladder Neoplasms Ferring Pharmaceuticals A/S 2022-12-16 Mesothelioma; Urinary Bladder Neoplasms Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Autologous CD34+-enriched hematopoietic stem and progenitor cells (Genenta Science) Phase 2 Clinical Genenta Science Srl Glioblastoma; Multiple Myeloma Details
CX-801 CX-801 Phase 1 Clinical Cytomx Therapeutics Inc Solid tumours; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Melanoma Details

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