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Your Position: Home > CLEC4C

CLEC4C

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Cat. No. Species Product Description Structure Purity Feature
CLC-H5245 Human Human CLEC4C / BDCA2 Protein, His Tag
CLC-H5245-structure
CLC-H5245-sds
CLC-C52H4 Cynomolgus Cynomolgus CLEC4C / BDCA2 Protein, His Tag (MALS verified)
CLC-C52H4-structure
CLC-C52H4-sds
CLC-H5254 Human Human CLEC4C / BDCA2 Protein, Fc Tag
CLC-H5254-structure
CLC-H5254-sds

Part of Bioactivity data

CLC-H5245-MALS-HPLC
Human CLEC4C, His Tag (Cat. No. ) MALS images

The purity of Human CLEC4C, His Tag (Cat. No. CLC-H5245) is more than 85% and the molecular weight of this protein is around 66-90 kDa verified by SEC-MALS.

  • Background
    CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

    CLC-C52H4-MALS-HPLC
    Cynomolgus CLEC4C, His Tag (Cat. No. ) MALS images

    The purity of Cynomolgus CLEC4C, His Tag (Cat. No. CLC-C52H4) is more than 90% and the molecular weight of this protein is around 59-80 kDa verified by SEC-MALS.

Synonym Name

DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL

Background

CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.

Clinical and Translational Updates

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