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Latent TGF-beta 2

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Cat. No. Species Product Description Structure Purity Feature
TG2-H5243 Human Human Latent TGF-beta 2 / TGFB2 Protein, His Tag
TG2-H5243-structure
TG2-H5243-sds
TG2-H5243-elisa_1

Part of Bioactivity data

TG2-H5243-ELISA
Human Latent TGFB2, His TagHuman Latent TGFB2, His Tag (Cat. No. TG2-H5243) ELISA bioactivity

Immobilized Human Latent TGFB2, His Tag (Cat. No. TG2-H5243) at 5 μg/mL (100 μL/well) can bind Human LRRC32, Fc Tag (Cat. No. LR2-H5256) with a linear range of 0.039-0.625 μg/mL (QC tested).

Synonym Name

Latent TGFB2,MGC116892,TGFβ2,TGF-beta2

Background

Transforming growth factor beta 2 ( TGFB2) is also known as TGF-β2, G-TSF, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The TGFB2 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self-destruction of cells (apoptosis). The TGFB2 protein can inhibit the T cell growth by IL-2-dependent. and can inhibit immune surveillance during tumor development, the protein promoting tumor growth with an autocrine manner. TGF-β2 can affect the viability of killer cells and reduce the expression of IL-2, IL-6, IL-10, IFN-γ and other cytokines.TGFB2 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages.

Clinical and Translational Updates

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