Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Sortilin


Brief Information

Target Synonym:100 kDa NT receptor,NT3,Glycoprotein 95,LDLCQ6,NTR3,Gp95,Sortilin 1,Neurotensin receptor 3
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 3 Clinical

Product ListCompare or Buy

ACRO Quality

Part of Bioactivity data

 Sortilin SPR

Biotinylated Human Sortilin Protein, His,Avitag (Cat. No. SON-H82E9) captured on Biotin CAP-Series S Sensor Chip can bind Human Progranulin Protein, His Tag (Cat. No. PGN-H52H3) with an affinity constant of 0.355 μM as determined in a SPR assay (Biacore 8K) (QC tested).

Sortilin MALS images

The purity of Biotinylated Human Sortilin Protein, His,Avitag (Cat. No. SON-H82E9) is more than 85% and the molecular weight of this protein is around 80-107 kDa verified by SEC-MALS.

Synonym Name

Sortilin,SORT1,100 kDa NT receptor,Glycoprotein 95,Gp95,Gp95LDLCQ6,Neurotensin receptor 3,NT3NTR3,Ntr3,sortilin 1,


The Sortilin is a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Latozinemab AL-001; GSK-4527223 Phase 3 Clinical Alector Inc, Glaxosmithkline Plc Bipolar Disorder; Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Neurodegenerative Diseases Details
VES-001 VES-001; VES001 Phase 1 Clinical Vesper Bio APS Frontotemporal Dementia Details

This web search service is supported by Google Inc.

Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
+1 888-377-6111
1 Innovation Way, Newark, DE 19711, USA

Leave a message