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Home PageAll MoleculesSortilin
Sortilin
Sortilin Overview
| English Name | Sortilin | Approved Drugs | 0 |
| Drugs in Clinical Trials | 3 | Target Synonym | 100 kDa NT receptor，NT3，Glycoprotein 95，LDLCQ6，NTR3，Gp95，Sortilin 1，Neurotensin receptor 3 |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | Sortilin |
| Target Synonym | 100 kDa NT receptor，NT3，Glycoprotein 95，LDLCQ6，NTR3，Gp95，Sortilin 1，Neurotensin receptor 3 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 3 |
| Highest Development Stage | Phase 2 Clinical |
Sortilin Product List
- Product Category
Protein (5)Cell (1)
- Product Status
Launched (6)
- Species
Human (3)Cynomolgus (1)Rat (1)Canine (1)
- Tag
His Tag (4)His Tag & Avi Tag (1)- (1)
- Conjugate
Unconjugated (4)Biotin-labeled (1)- (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
CHEK-ATP155 |  Human | HEK293 | HEK293/Human SORT1 Stable Cell Line |  |  Add to Cart | ||
SON-H52H5 | Human | HEK293 | Human Sortilin / SORT1 Protein, His Tag, low endotoxin (MALS verified) |  |  | Add to Cart | |
SON-H82E9 | Human | HEK293 | Biotinylated Human Sortilin / SORT1 Protein, His,Avitag™ (MALS & SPR verified) |  | |  | Add to Cart |
SON-C52H3 |  Cynomolgus | HEK293 | Cynomolgus Sortilin Protein, His Tag |  | | Add to Cart | |
SON-C52H4 |  Canine | HEK293 | Canine Sortilin Protein, His Tag |  | | Add to Cart | |
SON-R52H3 |  Rat | HEK293 | Rat Sortilin Protein, His Tag (MALS verified) |  | | Add to Cart |
Total: 6
- 1
Sortilin Background
Sortilin is a multifunctional type-I transmembrane protein belonging to the Vps10p-domain receptor family (Vps10p-Domain Receptors, Vps10p-DRs). Sortilin plays a central role in cellular protein sorting, signal transduction, and metabolism. Its dysfunction is closely related to neurodegenerative diseases, metabolic syndrome, and cancer, and it is a potential therapeutic target for diseases.
Sortilin Synonyms
Sortilin,SORT1,100 kDa NT receptor,Glycoprotein 95,Gp95,Gp95LDLCQ6,Neurotensin receptor 3,NT3NTR3,Ntr3,sortilin 1,
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| VES-001 | VES001; VES-001 | Phase 2 Clinical | Vesper Bio APS | Dementia; Frontotemporal Dementia; Frontotemporal Lobar Degeneration | Details |
| Latozinemab | AL-001; GSK-4527223 | Phase 1 Clinical | Alector Inc, Glaxosmithkline Plc | Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Neurodegenerative Diseases | Details |
| ARB-1-6 | ARB-1-6; PQ-203 | Phase 1 Clinical | ProteinQure Inc | Breast Neoplasms; Solid tumours; Triple Negative Breast Neoplasms | Details |
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