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Your Position: Home > BST1

BST1

Brief Information

Name:ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
Target Synonym:Bone Marrow Stromal Cell Antigen 1 Variant 2,BST1,Bone marrow stromal antigen 1,Bone Marrow Stromal Cell Antigen 1,ADP-Ribosyl Cyclase 2,Cyclic ADP-Ribose Hydrolase 2,NAD(+) Nucleosidase,CADPr Hydrolase 2,ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2,CD157 Antigen,EC 3.2.2.6,CD157,BST-1,EC:3.2.2.6
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Cat. No. Species Product Description Structure Purity Feature
BS1-H52H9 Human Human BST1 Protein, His Tag (MALS verified)
BS1-H52H9-structure
BS1-H52H9-sds
ACRO Quality

Part of Bioactivity data

BS1-H52H9-MALS-HPLC
Human BST1, His Tag (Cat. No. ) MALS images

The purity of Human BST1, His Tag (Cat. No. BS1-H52H9) is more than 90% and the molecular weight of this protein is around 80-95 kDa verified by SEC-MALS.

Report
  • Background
    Bone marrow stromal cell antigen-1(BST-1) or CD157 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that belongs to the CD38 family. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth.BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
  • Clinical and Translational Updates
      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

ADP-ribosyl cyclase 2, CD157

Background

Bone marrow stromal cell antigen-1(BST-1) or CD157 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that belongs to the CD38 family. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth.BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
OBT-357 OX-001; OX-357; OBT-357; MEN-1112 Phase 1 Clinical Menarini, Oxford Biomedica Leukemia, Myeloid, Acute Details
OBT-357 OX-001; OX-357; OBT-357; MEN-1112 Phase 1 Clinical Menarini, Oxford Biomedica Leukemia, Myeloid, Acute Details

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