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Brief Information

Name:Monoamine oxidase B
Target Synonym:EC:,EC 1.4.3,MAOB,Amine oxidase [flavin-containing] B,Monoamine Oxidase B,Monoamine Oxidase Type B,MAO-B,Adrenalin Oxidase,Tyramine Oxidase,MAO, Platelet,MAO, Brain,EC
Number of Launched Drugs:4
Number of Drugs in Clinical Trials:8
Lastest Research Phase:Approved
ACRO Quality

Synonym Name

MAO-B,Monoamine Oxidase B


Monoamine Oxidase Type B (MAOB) is an enzyme located in the outer mitochondrial membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the breakdown of dopamine in the brain. MAOB inhibitors, that reduces dopamine turnover, are in clinical use for the treatment of Parkinson's disease (PD).

Clinical and Translational Updates

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