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Brief Information

Name:Somatostatin receptor 2
Target Synonym:Somatostatin receptor type 2,SS-2-R,SS2R,SSTR2,Somatostatin Receptor 2,SRIF-1,SS2-R
Number of Launched Drugs:6
Number of Drugs in Clinical Trials:17
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
SS2-HF2G3 Human Fluorescent Human SSTR2 Full Length Protein (VLP)
SS2-H5216 Human Human SSTR2 Full Length Protein (VLP)
ACRO Quality

Part of Bioactivity data


Immobilized Human SSTR2 Full Length Protein-VLP (Cat. No. SS2-H5216) at 5 μg/mL (100 μL/well) can bind Anti-SSTR2 Antibody, Human IgG1 with a linear range of 0.3-5 ng/mL (QC tested).


Immobilized Fluorescent Human SSTR2 Full Length Protein (VLP) (Cat. No. SS2-HF2G3) at 1 μg/mL (100 μL/well) can bind Anti-SSTR2 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

Synonym Name

Smstr2,Somatostatin R2,somatostatin receptor 2,somatostatin receptor type 2,SomatostatinR2,SRIF-1,SS2R,SS-2-R,SS2-R,SST2,SSTR2


Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Pasireotide Pamoate Approved Novartis Pharma Ag Signifor lar United States Acromegaly Recordati Rare Diseases Inc 2014-12-15 Gigantism; Acromegaly; Cushing Syndrome; Carcinoid Tumor; Pituitary ACTH Hypersecretion; Neuroendocrine Tumors; Meningioma Details
Lutetium (177Lu) oxodotreotide [Lu-177]-DOTATATE; AAA-601; XTR-008; 177Lu-DOTATATE; Lu-DOTATATE; F-1515 Approved Advanced Accelerator Applications Sa Lutathera EU Neuroendocrine Tumors Advanced Accelerator Applications Sa 2017-09-26 Prostatic Neoplasms; Carcinoid Heart Disease; Meningioma; Paraganglioma; Gastrointestinal Neoplasms; Carcinoma, Neuroendocrine; Lung Neoplasms; Pituitary Neoplasms; Breast Neoplasms; Neuroblastoma; Medullary thyroid cancer (MTC); Leiomyosarcoma; Neuroendocrine Tumors; Pancreatic Neoplasms; Adenoma, Islet Cell; Malignant Carcinoid Syndrome; Pancreatic neuroendocrine tumors (pNET); Carcinoid Tumor; Bronchial Neoplasms; Pheochromocytoma; Stomach Neoplasms; Liver Neoplasms Details
Vapreotide Acetate RC-160; BMY-41606 Approved Debiopharm Group Sanvar, Docrised, Sanvar IR, Sanvar SR Acromegaly; Hypertension, Portal; Pancreatic Neoplasms; Hemorrhage; Neuroendocrine Tumors; Diarrhea; Intraoperative Complications; Postoperative Complications; Esophageal and Gastric Varices; Crohn Disease Details
Pasireotide Diaspartate SOM-230; SOM-230C; SOM-320 Approved Novartis Pharma Ag Signifor, 丝尼芬 EU Cushing Syndrome Recordati Rare Diseases Inc 2012-04-24 Pituitary Neoplasms; Uveal melanoma; Prostatic Neoplasms, Castration-Resistant; Cysts; Pituitary ACTH Hypersecretion; Medullary thyroid cancer (MTC); Prostatic Neoplasms; Hyperinsulinism; Nelson Syndrome; Multiple Myeloma; Thyroid Neoplasms; Thymoma; Meningioma; Prolactinoma; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular; Cluster Headache; Acromegaly; Neuroendocrine Tumors; Liver Cirrhosis; Kidney Diseases; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Neoplasms; Adenoma, Islet Cell; Hypoglycemia; Dumping Syndrome; Insulinoma; Carcinoid Tumor; Cushing Syndrome; Alcohol-Induced Disorders; Congenital Hyperinsulinism; ACTH Syndrome, Ectopic Details
Ga-68 Edotreotide SMT-487; [68Ga]DOTATOC; 90Y-DOTATOC Approved Advanced Accelerator Applications Sa SomaKit TOC, Gallium Dotatoc Ga 68, TOCscan EU Diagnostic agents; Neuroendocrine Tumors; Pancreatic neuroendocrine tumors (pNET) Advanced Accelerator Applications Sa 2016-12-08 Medulloblastoma; Multiple Endocrine Neoplasia Type 1; Carcinoid Tumor; Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors; Neuroblastoma; Pituitary Neoplasms; Diagnostic agents; von Hippel-Lindau Disease; Somatostatinoma; Meningioma; Paraganglioma Details
Gallium (68Ga) oxodotreotide 68Ga-DOTA-TATE; 68-Ga-DOTA-TATE Approved Advanced Accelerator Applications Sa Netspot United States Neuroendocrine Tumors Aaa Usa Inc 2016-06-01 Pheochromocytoma; Carcinoid Tumor; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neuroendocrine Tumors; Prostatic Neoplasms; Thyroid Neoplasms; Carcinoma, Neuroendocrine; von Hippel-Lindau Disease; Paraganglioma; Carcinoma, Hepatocellular Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Paltusotine CRN-00808 Phase 3 Clinical Crinetics Pharmaceuticals Inc Acromegaly; Malignant Carcinoid Syndrome; Neuroendocrine Tumors Details
Lutetium-177 labelled edotreotide ITM-11 Phase 3 Clinical Universitaetsspitals Basel, Itm Solucin Gmbh Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors; Thymus Neoplasms; Lung Neoplasms Details
RYZ-101 RYZ-101 Phase 3 Clinical Carcinoid Tumor; Stomach Neoplasms; Pancreatic neuroendocrine tumors (pNET); Small Cell Lung Carcinoma; Neuroendocrine Tumors; Carcinoma, Neuroendocrine; Gastrointestinal Neoplasms Details
Gallium-68 satoreotide 68Ga-OPS-202; 68Ga IPN-1070; 68Ga-DOTA-JR11 Phase 2 Clinical Ipsen Inc Stomach Neoplasms; Pancreatic neuroendocrine tumors (pNET); Small Cell Lung Carcinoma; Breast Neoplasms; Gastrointestinal Neoplasms Details
Nendratareotide uzatansine BTP-277; PEN-221 Phase 2 Clinical Tarveda Therapeutics Inc Small Cell Lung Carcinoma; Neuroendocrine Tumors; Carcinoma, Neuroendocrine Details
Yttrium 90-labelled edotreotide SMT-487-[90Y]; DOTATOC-[90Y] Phase 2 Clinical The University Of Iowa, Novartis Pharma Ag Central Nervous System Neoplasms; Meningioma; Melanoma; Lymphoma; Lung Neoplasms; Sarcoma; Neuroblastoma; Breast Neoplasms; Brain Neoplasms; Solid tumours; Neuroendocrine Tumors; Small Cell Lung Carcinoma; Adenoma, Islet Cell; Neoplasms; Pheochromocytoma; Carcinoid Tumor; Medulloblastoma Details
Dopastatin TBR-760; BIM-23A760 Phase 2 Clinical Ipsen Acromegaly; Malignant Carcinoid Syndrome; Adenoma; Pituitary Neoplasms Details
ZT-01 ZT 01; ZT-01 Phase 2 Clinical Tulane University, York University, University Of Toronto, Toronto Diabetes Mellitus, Type 1; Hypoglycemia Details
Re-188 P 2045 P2045; BAY-865284; Rhenium-188 P2045; Re-188 P 2045; Rh-188 P2045; Rhenium-188-P-2045 Phase 2 Clinical Bayer AG Neoplasm Recurrence, Local; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Lung Neoplasms; Carcinoma, Small Cell; Carcinoma, Non-Small-Cell Lung Details
64Cu-SarTate Phase 2 Clinical University Of Melbourne Neuroendocrine Tumors; Neuroblastoma; Meningioma Details
Lutetium-177 DOTA satoreotide [177Lu]LuSSO110; 177Lu-IPN-1072; OPS-201; 177Lu-IPN01072; 177LU-OPS 201; 177Lu-DOTA- JR11; 177Lu-satoreotide Phase 1 Clinical Ipsen, OctreoPharm Sciences GmbH Small Cell Lung Carcinoma; Breast Neoplasms; Meningioma Details
CRN-01941 CRN-01941 Phase 1 Clinical Crinetics Pharmaceuticals Inc Details
68Ga-NOTA-3PTATE-RGD 68Ga-NOTA-3PTATE-RGD; 68Ga-NOTA-3P-TATE-RGD Phase 1 Clinical Peking Union Medical College Hospital Small Cell Lung Carcinoma; Neuroendocrine Tumors; Lung Neoplasms Details
[99mTc]Tc-TECANT1 Phase 1 Clinical Ljubljana University Medical Centre, Medical University Of Innsbruck, Narodowe Centrum Badan Jadrowych, Jagiellonian University Sylff Fellows Association Neuroendocrine Tumors Details
161Tb-DOTA-LM3 161Tb-DOTA-LM3 Phase 1 Clinical University Hospital Basel Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors Details
[203-Pb] VMT-NET [203-Pb] VMT-NET Phase 1 Clinical Perspective Therapeutics Inc Neuroendocrine Tumors Details
44Sc-edotreotide 44Sc-edotreotide; 44Sc-DOTA-[3-Tyr]-octreotide; Sc44-DOTATOC Clinical Zentralklinik Bad Berka Diagnostic agents Details

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