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A29L

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Cat. No. Species Product Description Structure Purity Feature
A2L-M577 Mouse Monoclonal Anti-Monkeypox-A29L Antibody, Human IgG1 (3H9) (MALS verified)
A2L-M577-sds
A2L-M52H3 Monkeypox virus (strain Zaire-96-I-16) Monkeypox virus (strain Zaire-96-I-16) A29L Protein, His Tag
A2L-M52H3-structure
A2L-M52H3-sds
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Part of Bioactivity data

A2L-M577-SPR
A29L SPR

Monoclonal Anti-Monkeypox-A29L Antibody, Human IgG1 (3H9) (Cat. No. A2L-M577) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) A29L Protein, His Tag (Cat. No. A2L-M52H3) with an affinity constant of 47.7 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
A2L-M52H3-ELISA
A29L ELISA

Immobilized Monkeypox virus (strain Zaire-96-I-16) A29L Protein, His Tag (Cat. No. A2L-M52H3) at 5 μg/mL (100 μL/well) can bind Anti-Monkeypox-A29L-Antibody with a linear range of 0.1-13 ng/mL (QC tested).

Protocol

Synonym Name

A29L

Background

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The cases are mostly in central and western Africa.  The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A29L binds to cell surface heparin to promote fusion of viral membrane with host plasma membrane.

Clinical and Translational Updates

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