Clusterin
Clusterin Molecule Information
Name:Clusterin
Target Synonym:Aging-associated gene 4 protein;Apo-J;Complement-associated protein SP-40,40;KUB1;Apolipoprotein J;Testosterone-repressed prostate message 2;CLI;Ku70-binding protein 1;Complement cytolysis inhibitor;CLU;APOJ;NA1/NA2
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase ?
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Clusterin Molecule Synonym Name
CLU,Clusterin,AAG4,APOJ,CLI,KUB1,SGP-2,SP-40,TRPM2
Clusterin Molecule Background
Clusterin (CLU) is also known as dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI), is a secreted multifunctional glycoprotein protein which belongs to the clusterin family. Intracellular cleavages of the precursor of clusterin remove the signal peptide and generate comparably sized ¦Á and ¦Â chains which are secreted as an 80 kDa N
Clusterin Clinical Drug Information
Name |
Research Code |
Research Phase |
Company |
Indications |
Clinical Trials |
AB-16B5 |
AB-16B5; 16B5; AB-sCLU mAB |
Phase Ⅱ |
National Research Council Biotechnology Research Institute, Alethia BioTherapeutics |
Non small cell lung cancer (NSCLC) |
Details
|
Custirsen Sodium |
ISIS-112989; OGX-011; TV-1011 |
Phase Ⅲ |
University of British Columbia, OncoGenex, Ionis |
Non small cell lung cancer (NSCLC), Prostate cancer |
Details
|