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Clusterin Molecule Information

Target Synonym:Aging-associated gene 4 protein;Apo-J;Complement-associated protein SP-40,40;KUB1;Apolipoprotein J;Testosterone-repressed prostate message 2;CLI;Ku70-binding protein 1;Complement cytolysis inhibitor;CLU;APOJ;NA1/NA2
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
CLU-H5227 Human Human Clusterin / CLUS Protein, His Tag

Clusterin Molecule Synonym Name


Clusterin Molecule Background

Clusterin (CLU) is also known as dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI), is a secreted multifunctional glycoprotein protein which belongs to the clusterin family. Intracellular cleavages of the precursor of clusterin remove the signal peptide and generate comparably sized ¦Á and ¦Â chains which are secreted as an 80 kDa N

Clusterin Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
AB-16B5 AB-16B5; 16B5; AB-sCLU mAB Phase Ⅱ National Research Council Biotechnology Research Institute, Alethia BioTherapeutics Non small cell lung cancer (NSCLC) Details
Custirsen Sodium ISIS-112989; OGX-011; TV-1011 Phase Ⅲ University of British Columbia, OncoGenex, Ionis Non small cell lung cancer (NSCLC), Prostate cancer Details

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