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| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| EDB-HF2G4 | Human | Fluorescent Human EDNRB Full Length Protein (VLP) |
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| EDB-H52P7 | Human | Human EDNRB Full Length Protein (VLP) |
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Immobilized Human EDNRB Full Length Protein-VLP (Cat. No. EDB-H52P7) at 5 μg/mL (100 μL/well) can bind Anti-EDNRB Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Sovateltide | IRL-1620; PMZ-1620; SPI-1620 | Approved | University Of Illinois At Chicago | Tyvalzi | India | Stroke | Pharmazz Inc | 2023-05-31 | Brain Ischemia; Biliary Tract Neoplasms; Carcinoma; Spinal Cord Injuries; Asphyxia Neonatorum; Brain Diseases; Stroke; Hypoxia-Ischemia, Brain; Dementia; Alzheimer Disease; Cerebral Infarction; Carcinoma, Non-Small-Cell Lung | Details |
| Macitentan/Tadalafil | Approved | Actelion Pharmaceuticals Ltd | OPSYNVI | United States | Pulmonary Arterial Hypertension | Actelion Pharmaceuticals Us Inc | 2024-03-22 | Pulmonary Arterial Hypertension | Details | |
| Bosentan Hydrate | ACT-050088; HGP-1206; Ro-47-0203; Ro-47-0203/029; Ro-47-0203/039 | Approved | F. Hoffmann-La Roche Ltd | Stayveer, 全可利, Tracleer | United States | Pulmonary Arterial Hypertension | Actelion Pharmaceuticals Ltd | 2001-11-20 | Pulmonary Fibrosis; Heart Defects, Congenital; Diabetes Mellitus; Anemia, Sickle Cell; Persistent Fetal Circulation Syndrome; Ulcer; Sleep Apnea Syndromes; Glaucoma; Pulmonary Arterial Hypertension; Hypertension; Hepatopulmonary Syndrome; Hypertension, Pulmonary; Lung Diseases, Interstitial; Sarcoidosis; Liver Cirrhosis; Chronic thromboembolic pulmonary hypertension; Fibrosis; Scleroderma, Systemic; Idiopathic Pulmonary Fibrosis; Diabetes Mellitus, Type 2; Heart Septal Defects, Atrial | Details |
| Macitentan | ACT-064992; Actelion-1; JNJ-67896062 | Approved | Actelion Pharmaceuticals Ltd | Zependo, Opsumit, 傲朴舒 | United States | Pulmonary Arterial Hypertension | Actelion Pharmaceuticals Us Inc | 2013-10-18 | Hypertension, Pulmonary; Pulmonary Embolism; Heart Failure; Idiopathic Pulmonary Fibrosis; Scleroderma, Systemic; Chronic thromboembolic pulmonary hypertension; Glioblastoma; Lung Diseases, Interstitial; Thromboembolism; Pulmonary Arterial Hypertension; Eisenmenger Complex; Ulcer; Anemia, Sickle Cell; Chronic Disease; Heart Defects, Congenital | Details |
| Aprocitentan | ACT-132577; AC-080; JNJ-2820 | Approved | Idorsia Pharmaceuticals Ltd, Actelion Pharmaceuticals Ltd | TRYVIO | United States | Hypertension | Idorsia Pharmaceuticals Ltd | 2024-03-19 | Hypertension; Hepatic Insufficiency; Essential Hypertension; Renal Insufficiency, Chronic | Details |
| Sovateltide | IRL-1620; PMZ-1620; SPI-1620 | Approved | University Of Illinois At Chicago | Tyvalzi | India | Stroke | Pharmazz Inc | 2023-05-31 | Brain Ischemia; Biliary Tract Neoplasms; Carcinoma; Spinal Cord Injuries; Asphyxia Neonatorum; Brain Diseases; Stroke; Hypoxia-Ischemia, Brain; Dementia; Alzheimer Disease; Cerebral Infarction; Carcinoma, Non-Small-Cell Lung | Details |
| Macitentan/Tadalafil | Approved | Actelion Pharmaceuticals Ltd | OPSYNVI | United States | Pulmonary Arterial Hypertension | Actelion Pharmaceuticals Us Inc | 2024-03-22 | Pulmonary Arterial Hypertension | Details | |
| Bosentan Hydrate | ACT-050088; HGP-1206; Ro-47-0203; Ro-47-0203/029; Ro-47-0203/039 | Approved | F. Hoffmann-La Roche Ltd | Stayveer, 全可利, Tracleer | United States | Pulmonary Arterial Hypertension | Actelion Pharmaceuticals Ltd | 2001-11-20 | Pulmonary Fibrosis; Heart Defects, Congenital; Diabetes Mellitus; Anemia, Sickle Cell; Persistent Fetal Circulation Syndrome; Ulcer; Sleep Apnea Syndromes; Glaucoma; Pulmonary Arterial Hypertension; Hypertension; Hepatopulmonary Syndrome; Hypertension, Pulmonary; Lung Diseases, Interstitial; Sarcoidosis; Liver Cirrhosis; Chronic thromboembolic pulmonary hypertension; Fibrosis; Scleroderma, Systemic; Idiopathic Pulmonary Fibrosis; Diabetes Mellitus, Type 2; Heart Septal Defects, Atrial | Details |
| Macitentan | ACT-064992; Actelion-1; JNJ-67896062 | Approved | Actelion Pharmaceuticals Ltd | Zependo, Opsumit, 傲朴舒 | United States | Pulmonary Arterial Hypertension | Actelion Pharmaceuticals Us Inc | 2013-10-18 | Hypertension, Pulmonary; Pulmonary Embolism; Heart Failure; Idiopathic Pulmonary Fibrosis; Scleroderma, Systemic; Chronic thromboembolic pulmonary hypertension; Glioblastoma; Lung Diseases, Interstitial; Thromboembolism; Pulmonary Arterial Hypertension; Eisenmenger Complex; Ulcer; Anemia, Sickle Cell; Chronic Disease; Heart Defects, Congenital | Details |
| Aprocitentan | ACT-132577; AC-080; JNJ-2820 | Approved | Idorsia Pharmaceuticals Ltd, Actelion Pharmaceuticals Ltd | TRYVIO | United States | Hypertension | Idorsia Pharmaceuticals Ltd | 2024-03-19 | Hypertension; Hepatic Insufficiency; Essential Hypertension; Renal Insufficiency, Chronic | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| VRP-1620 | VRP-1620 | Phase 3 Clinical | University Of Illinois | Breast Neoplasms | Details |
| ENB-003 | ENB-003 | Phase 2 Clinical | Enb Therapeutics Inc | Ovarian Neoplasms; Solid tumours; Neoplasms; Pancreatic Neoplasms; Melanoma | Details |
| BQ-788 | BQ-788 | Phase 1 Clinical | Merck Serono | Hypertension; Cardiovascular Diseases; Melanoma | Details |
| VRP-1620 | VRP-1620 | Phase 3 Clinical | University Of Illinois | Breast Neoplasms | Details |
| ENB-003 | ENB-003 | Phase 2 Clinical | Enb Therapeutics Inc | Ovarian Neoplasms; Solid tumours; Neoplasms; Pancreatic Neoplasms; Melanoma | Details |
| BQ-788 | BQ-788 | Phase 1 Clinical | Merck Serono | Hypertension; Cardiovascular Diseases; Melanoma | Details |
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