CNTF R alpha Protein - ACROBiosystems

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CNTF R alpha

Brief Information

Name:Ciliary neurotrophic factor receptor
Target Synonym:CNTFR,Ciliary Neurotrophic Factor Receptor,CNTF Receptor Subunit Alpha,CNTFR-Alpha,Receptor, Ciliary Neurotrophic Factor,Ciliary Neurotrophic Factor Receptor Subunit Alpha

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 3 Clinical


CNR-H5225	Human	Human CNTF R alpha Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

CNR-H5225

Human

Human CNTF R alpha Protein, His Tag

Synonym Name

CNTFR,CNTF R alpha

Background

Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.

Clinical and Translational Updates

Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Ciliary neurotrophic factor (Neurotech)	NT-501	Phase 3 Clinical	Neurotech Pharmaceuticals, National Eye Institute, Stanford University, University Of Miami	Telangiectasis; Retinitis Pigmentosa; Usher Syndromes; Macular Degeneration	Details