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CNTF R alpha

Brief Information

Name:Ciliary neurotrophic factor receptor
Target Synonym:CNTFR,Ciliary Neurotrophic Factor Receptor,CNTF Receptor Subunit Alpha,CNTFR-Alpha,Receptor, Ciliary Neurotrophic Factor,Ciliary Neurotrophic Factor Receptor Subunit Alpha
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 3 Clinical

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Cat. No. Species Product Description Structure Purity Feature
CNR-H5225 Human Human CNTF R alpha Protein, His Tag
CNR-H5225-structure
CNR-H5225-sds

Synonym Name

CNTFR,CNTF R alpha

Background

Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Ciliary neurotrophic factor (Neurotech) NT-501 Phase 3 Clinical Neurotech Pharmaceuticals, National Eye Institute, Stanford University, University Of Miami Telangiectasis; Retinitis Pigmentosa; Usher Syndromes; Macular Degeneration Details

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