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IDO1

Brief Information

Name:Indoleamine 2,3-dioxygenase
Target Synonym:Indoleamine-pyrrole 2,3-dioxygenase,IDO1,IDO-1,INDO,IDO,Indoleamine-Pyrrole 2,3 Dioxygenase,Indole 2,3-Dioxygenase,EC 1.13.11.52,Indoleamine-Pyrrole 2,3,-Dioxygenase,Indoleamine 2,3-Dioxygenase 1,Indolamine 2,3 Dioxygenase,EC:1.13.11.52
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:11
Lastest Research Phase:Phase 3 Clinical

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Cat. No. Species Product Description Structure Purity Feature
ID1-H5143 Human Human IDO1 Protein, His Tag (active enzyme, MALS verified)
ID1-H5143-structure
ID1-H5143-sds
ACRO Quality

Part of Bioactivity data

The purity of Human IDO1 Protein, His Tag (Cat. No. ID1-H5143) is more than 85% and the molecular weight of this protein is around 40-60 kDa verified by SEC-MALS.

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Epacadostat INCB-024360; 71596A9R13 (UNII code); INCB-24360 Phase 3 Clinical Incyte Corp Esophageal Squamous Cell Carcinoma; Sarcoma; Nasopharyngeal Carcinoma; Gastrointestinal Stromal Tumors; Peritoneal Neoplasms; Colorectal Neoplasms; Thymus Neoplasms; Leukemia, B-Cell; Lymphoma; Endometrial Neoplasms; Esophageal adenocarcinoma; Lung Neoplasms; Urethral Neoplasms; Carcinoma, Pancreatic Ductal; Fallopian Tube Neoplasms; Thymoma; Glioma; Carcinoma, Squamous Cell; Urogenital Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular; Neoplasm Metastasis; Pancreatic Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Lymphoma, B-Cell; Skin Melanoma; Esophageal Neoplasms; Abdominal Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Carcinoma, Ovarian Epithelial; Solid tumours; Carcinoma, Transitional Cell; Triple Negative Breast Neoplasms; Glioblastoma; Myelodysplastic Syndromes; Small Cell Lung Carcinoma; Neoplasms; Nasopharyngeal Neoplasms; Urinary Bladder Neoplasms; Uveal melanoma; Prostatic Neoplasms Details
Puliginurad YL-90148 Phase 3 Clinical YL-Pharma Hyperuricemia; Gout Details
Linrodostat ONO-7701; BMS-986205 Phase 3 Clinical Bristol-Myers Squibb Company Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Skin Neoplasms; Glioblastoma; Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Mouth Neoplasms; Lung Neoplasms; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung; Laryngeal Diseases; Melanoma; Carcinoma, Hepatocellular Details
IO-102 IO-102 Phase 2 Clinical Herlev Hospital, Merck Sharp & Dohme Corp, Io Biotech Aps Carcinoma, Squamous Cell; Mouth Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma Details
Indoximod 1-MT; D-1MT; NLG-001; NLG-8189; NSC-721782 Phase 2 Clinical Newlink Genetics Co Brain Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Glioma; Leukemia, Myeloid, Acute; Lung Neoplasms; Metastatic breast cancer; Gliosarcoma; Diffuse Intrinsic Pontine Glioma; Medulloblastoma; Breast Neoplasms; Prostatic Neoplasms; Central Nervous System Neoplasms; Glioblastoma; Pancreatic Neoplasms; Solid tumours; Ependymoma Details
RiMO-301 RiMO-301 Phase 2 Clinical The University Of Chicago Head and Neck Neoplasms; Neoplasms Details
SHR-9146 HTI-1090; SHR-9146 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Solid tumours; Neoplasms Details
LPM-3480226 LY-01013; LPM-3480226 Phase 1 Clinical Luye Pharma Group Ltd Solid tumours Details
MK-7162 MK-7162 Phase 1 Clinical Merck Sharp & Dohme Corp Solid tumours Details
RiMO-401 RiMO-401 Phase 1 Clinical Coordination Pharmaceuticals Inc Solid tumours Details

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