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Brief Information

Name:Retinoid isomerohydrolase
Target Synonym:EC:,Retinoid isomerohydrolase,All-trans-retinyl-palmitate hydrolase,Retinal pigment epithelium-specific 65 kDa protein,RPE65,RPE65, Retinoid Isomerohydrolase,Retinol Isomerase,Retinal Pigment Epithelium-Specific Protein 65kDa,EC,Retinoid Isomerohydrolase RPE65,Retinal Pigment Epithelium Specific Protein 65,EC 5.3.3.-,EC:,Lutein Isomerase,Meso-Zeaxanthin Isomerase,BCO Family, Member 3,Retinitis Pigmentosa 20 (Autosomal Recessive),RBP-Binding Membrane Protein,EC,M
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
RP5-H52H3 Human Human RPE65 Protein, His Tag
ACRO Quality

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Voretigene neparvovec-rzyl 2SPI046IKD; rAAV.hRPE65v2; AAV2-hRPE65v2; SPKRPE-65; rAAV2-CBSB-hRPE65; AAV2.RPE65 Approved The Children'S Hospital Of Philadelphia Luxturna United States Retinal Dysplasia Spark Therapeutics Inc 2017-12-19 Vision Disorders; Retinal Dystrophies; Leber Congenital Amaurosis; Retinal Dysplasia Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Emixustat Hydrochloride ACU-02; ACU-4429; ACU-4429 HCl Phase 3 Clinical Acucela Inc Anetoderma; Geographic Atrophy; Stargardt Disease; Macular Degeneration; Diabetic Retinopathy Details
HG-004 HG-004 Phase 2 Clinical HuiGene Therapeutics Ltd Leber Congenital Amaurosis; Retinal Diseases Details
HORA-RPE65 (Horama) HORA-RPE65 Phase 2 Clinical Horama Sa Leber Congenital Amaurosis Details
LX-101 LX-101 Phase 3 Clinical Shanghai Langsheng Biological Technology Co Ltd Retinal Dysplasia; Retinal Degeneration Details

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