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Complement C1s

Brief Information

Name:Complement C1s
Target Synonym:EC:,EC 3.4.21,C1 esterase,Complement component 1 subcomponent s,C1S,Complement C1s,Complement Component 1, S Subcomponent,Basic Proline-Rich Peptide IB-1,Complement C1s Subcomponent,EC,EDSPD2
Number of Launched Drugs:4
Number of Drugs in Clinical Trials:5
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
COS-H52H3 Human Human Complement C1s Protein, His Tag
ACRO Quality

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Conestat alfa rhC1-INH Approved Pharming Group Nv Rhucin, Esterasine, Ruconest EU Angioedemas, Hereditary Pharming Group Nv 2010-10-28 Rejection of renal transplantation; Myocardial Infarction; Renal Insufficiency; Rejection of organ transplantation; Genetic Diseases, Inborn; Coronavirus Infections; Angioedema; Angioedemas, Hereditary Details
Sutimlimab BIVV-009; TNT-009 Approved True North Therapeutics ENJAYMO United States Anemia, Hemolytic, Autoimmune Bioverativ Therapeutics Inc 2022-02-04 Hemolysis; Purpura, Thrombocytopenic, Idiopathic; Anemia, Hemolytic, Autoimmune; Pemphigoid, Bullous; Kidney Failure, Chronic Details
C1 esterase inhibitor (Human, CSL Behring) BI-3.012; CSL-830; CSL-842; CE-1145 Approved Csl Behring Llc Berinert, Haegarda, Berinert 2000 Japan Angioedemas, Hereditary Csl Behring Llc 1990-06-29 Hereditary Angioedema Types I and II; Angioedemas, Hereditary Details
Complement C1 inhibitor protein (Shire ViroPharma) C1 INH-nf; C1-INH; SHP-616 Approved Sanquin Plasma Products Bv Cinryze, Cetor United States Angioedemas, Hereditary null 2008-10-10 Brain Injuries, Traumatic; Rejection of organ transplantation; Angioedemas, Hereditary Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
DNTH-103 DNTH-103; DNTH103 Phase 1 Clinical Dianthus Therapeutics Inc Autoimmune Diseases Details
Riliprubart SAR-445088; TNT-020; BIVV-020 Phase 2 Clinical Bioverativ Inc Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Purpura, Thrombocytopenic, Idiopathic; Polyneuropathies; Rejection of organ transplantation; Anemia, Hemolytic Details
C1 esterase inhibitor (Chengdu Institute of Biological Products) Phase 1 Clinical Chengdu Institute Of Biological Products Co Ltd Angioedemas, Hereditary Details
Complement-C1 inhibitor protein (Octapharma) Phase 2 Clinical Octapharma Angioedemas, Hereditary Details
C1 esterase inhibitor (Boya Bio-Pharmaceutical) Phase 3 Clinical Boya Bio-Pharmaceutical Group Co Ltd Angioedemas, Hereditary Details

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